Literature summary for 2.4.1.65 extracted from

Weston, B.W.; Nair, R.P.; Larsen, R.D.; Lowe, J.B.
Isolation of a novel human alpha (1,3)fucosyltransferase gene and molecular comparison to the human Lewis blood group alpha (1,3/1,4)fucosyltransferase gene. Syntenic, homologous, nonallelic genes encoding enzymes with distinct acceptor substrate specificities (1992), J. Biol. Chem., 267, 4152-4160.

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in COS cells	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
GDP-L-fucose + 2'-fucosyllactose	254% of the activity with Galbeta(1,4)GlcNAc	Homo sapiens	GDP + ?	-	?
GDP-L-fucose + alpha(2,3)-sialyllactosamine	56% of the activity with Galbeta(1,4)GlcNAc	Homo sapiens	GDP + ?	-	?
GDP-L-fucose + Galbeta(1,3)GlcNAc	420% of the activity with Galbeta(1,4)GlcNAc	Homo sapiens	GDP + Galbeta(1,3)(Fucalpha(1,4))GlcNAc	-	?
GDP-L-fucose + Galbeta(1,4)Glc	145% of the activity with Galbeta(1,4)GlcNAc	Homo sapiens	GDP + Galbeta(1,4)(Fucalpha(1,3))Glc	-	?

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Release 2023.1 (January 2023)