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Literature summary for 2.4.1.47 extracted from

  • Tencomnao, T.; Yu, R.K.; Kapitonov, D.
    Characterization of the human UDP-galactose:ceramide galactosyltransferase gene promoter (2001), Biochim. Biophys. Acta, 1517, 416-423.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
transcriptional regulation of the CGT gene, 2.3 kb CGT promoter Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDPgalactose + 2-(2-hydroxyacyl)sphingosine Homo sapiens key enzyme in the biosynthesis of galactocerebroside, the most abundant glycosphingolipid in the myelin sheath 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine + UDP galactocerebroside ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
glioma cell N-370 FG cells Homo sapiens
-
LAN5 cell neuroblastoma cell line Homo sapiens
-
oligodendroglioma cell HOG cell line Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDPgalactose + 2-(2-hydroxyacyl)sphingosine
-
Homo sapiens 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine + UDP
-
?
UDPgalactose + 2-(2-hydroxyacyl)sphingosine key enzyme in the biosynthesis of galactocerebroside, the most abundant glycosphingolipid in the myelin sheath Homo sapiens 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine + UDP galactocerebroside ?