Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
soluble | isozyme ppGalNAc T1 | Bos taurus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferases transfer GalNAc from UDP-GalNAc to the Ser and Thr residues of polypeptide acceptors, and initiate and regulate mucin-type O-glycosylation | ? | - |
? | |
additional information | Bos taurus | UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferases transfer GalNAc from UDP-GalNAc to the Ser and Thr residues of polypeptide acceptors, and initiate and regulate mucin-type O-glycosylation | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
isozyme ppGalNAc T1 | - |
Homo sapiens | - |
isozymes ppGalNAc T2 and ppGalNAc T10 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferases transfer GalNAc from UDP-GalNAc to the Ser and Thr residues of polypeptide acceptors, and initiate and regulate mucin-type O-glycosylation | Homo sapiens | ? | - |
? | |
additional information | UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferases transfer GalNAc from UDP-GalNAc to the Ser and Thr residues of polypeptide acceptors, and initiate and regulate mucin-type O-glycosylation | Bos taurus | ? | - |
? | |
UDP-N-acetyl-D-galactosamine + GAGAPGPTPGPAGAGK | optimal isozyme ppGalNAc T2 peptide substrate | Homo sapiens | UDP + GAGAPGP-(N-acetyl-D-galactosaminylT)-PGPAGAGK | - |
? | |
UDP-N-acetyl-D-galactosamine + osteopontin | isozyme ppGalNAc T10 prefers previously glycosylated peptides as substrates, ppGalNAc T10 exhibits a single large preference for Ser/Thr-O-GalNAc at the +1, C-terminal, position relative to the Ser or Thr acceptor site | Homo sapiens | UDP + N-acetyl-D-galactosaminyl-osteopontin | - |
? | |
UDP-N-acetyl-D-galactosamine + polypeptide | usage of random peptide substrates, overview. Isozyme substrate specificities, amino acid residue enhancement factors for ppGalNAc T isozymes are obtained from random peptide substrates, detailed overview | Homo sapiens | UDP + N-acetyl-D-galactosaminyl-polypeptide | product analysis by NMR and mass spectrometry | ? | |
UDP-N-acetyl-D-galactosamine + polypeptide | usage of random peptide substrates, overview. Isozyme substrate specificity, amino acid residue enhancement factors for the ppGalNAc T isozyme are obtained from random peptide substrates, detailed overview | Bos taurus | UDP + N-acetyl-D-galactosaminyl-polypeptide | product analysis by NMR and mass spectrometry | ? |
Synonyms | Comment | Organism |
---|---|---|
glycopeptide-preferring polypeptide GalNAc transferase 10 | - |
Homo sapiens |
glycopeptide-preferring polypeptide GalNAc transferase 10 | - |
Bos taurus |
More | the enzyme belongs to the large family of UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferases, ppGalNAc Ts | Homo sapiens |
More | the enzyme belongs to the large family of UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferases, ppGalNAc Ts | Bos taurus |
ppGalNAc T1 | - |
Bos taurus |
ppGalNAc T10 | - |
Homo sapiens |
ppGalNAc T2 | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
37 | - |
assay at | Bos taurus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.8 | - |
assay at | Homo sapiens |
7.8 | - |
assay at | Bos taurus |