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Literature summary for 2.4.1.41 extracted from

  • Wandall, H.H.; Irazoqui, F.; Tarp, M.A.; Bennett, E.P.; Mandel, U.; Takeuchi, H.; Kato, K.; Irimura, T.; Suryanarayanan, G.; Hollingsworth, M.A.; Clausen, H.
    The lectin domains of polypeptide GalNAc-transferases exhibit carbohydrate-binding specificity for GalNAc: lectin binding to GalNAc-glycopeptide substrates is required for high density GalNAc-O-glycosylation (2007), Glycobiology, 17, 374-387.
    View publication on PubMed
Search for more literature for 2.4.1.41

Application

Application Comment Organism
molecular biology enzyme-linked lectin assay (ELLA) as carbohydrate-binding assay Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
in pAcGP67-His vector for amplification as bacculovirus in Sf9 cells and subsequent infection of High Five cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
GalNAc-T2 lectin domain amino acids 405 to 578 of GalNAc-T2, lower expression level than full-length enzyme Homo sapiens
GalNAc-T2-D224H mutation in DXH nucleotide-binding motif, inactive mutant Homo sapiens
GalNAc-T2-D458H mutation in CLD motif of alpha repeat, impaired lectin-mediated MUC1 and GalNAc-MUC1 binding, no impaired specific activity, incorporates 1-2 fewer GalNAc residues per substrate molecule in endpoint reactions, no utilization of partially GalNAc-glycosylated peptides, higher KM for IgA hinge-4GalNAc Homo sapiens
GalNAc-T2-D541A mutation in CLD motif of gamma repeat Homo sapiens
GalNAc-T4 lectin domain amino acids 432 to 571 of GalNAc-T4, lower expression level than full-length enzyme Homo sapiens
GalNAc-T4 lectin domain-D459H mutation in CLD motif of alpha repeat Homo sapiens
GalNAc-T4-D459H mutation in CLD motif of alpha repeat, impaired lectin-mediated MUC1 and GalNAc-MUC1 binding Homo sapiens

General Stability

General Stability Organism
23% loss of specific activity after 12h shaking at 37°C Homo sapiens
25% loss of specific activity after 12 h shaking at 37°C Homo sapiens
31% loss of specific activity after 12h shaking at 37°C Homo sapiens
mutant GalNAc-T2-D458H: 15% loss of specific activity after 12h shaking at 37°C Homo sapiens
mutant GalNAc-T2-D541A: 19% loss of specific activity after 12h shaking at 37°C Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
benzyl-alpha-GalNAc
-
 Homo sapiens
D-galactose
-
 Homo sapiens
EDTA GalNAc-T4 enzyme and lectin domain; inhibition of GalNAc-T2 enzyme and lectin domain Homo sapiens
GalNAc inhibition for GalNAc-T2 lectin domain to bind GalNAc-MUC1; inhibition for GalNAc-T4 lectin domain to bind GalNAc-MUC1 Homo sapiens
methyl-alpha-Gal
-
 Homo sapiens
methyl-beta-Gal
-
 Homo sapiens
additional information benzyl or phenyl alpha and beta-GalNAc compounds show higher inhibition for GalNAc-T2 to bind GalNAc-MUC1 than for isoform GalNAc-T4. No inhibition of GalNAc-T2 enzyme and lectin domain by glucose, GlcNAc or mannose; benzyl or phenyl alpha and beta-GalNAc compounds show weaker inhibition for GalNAc-T4 to bind GalNAc-MUC1 than for isoform GalNAc-T2. No inhibition of GalNAc-T4 enzyme and lectin domain by glucose, GlcNAc or mannose Homo sapiens
o-nitrophenyl-alpha-GalNAc
-
 Homo sapiens
o-nitrophenyl-beta-GalNAc
-
 Homo sapiens
p-nitrophenyl-alpha-GalNAc
-
 Homo sapiens
p-nitrophenyl-beta-GalNAc
-
 Homo sapiens
phenyl-alpha-GalNAc
-
 Homo sapiens
UDP-alpha-GalNAc
-
 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.01
-
 Muc2 +/-0.001 mM, pH7.4 Homo sapiens
0.01
-
 IgA hinge +/-0.01 mM, mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
0.011
-
 UDP-GalNAc +/-0.002 mM, pH7.4 Homo sapiens
0.013
-
 UDP-GalNAc +/-0.001 mM, mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
0.015
-
 IgA hinge +/-0.002 mM, pH7.4 Homo sapiens
0.018
-
 Muc2 +/-0.003 mM, mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
0.02
-
 IgA hinge +/-0.005 mM, mutant GalNAc-T2-D458H, pH7.4 Homo sapiens
0.03
-
 UDP-GalNAc +/-0.001 mM, mutant GalNAc-T2-D458H, pH7.4 Homo sapiens
0.03
-
 UDP-Gal +/-0.002 mM, pH7.4 Homo sapiens
0.036
-
 UDP-Gal +/-0.001 mM, mutant GalNAc-T2-D458H, pH7.4 Homo sapiens
0.041
-
 UDP-Gal +/-0.005 mM, mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
0.062
-
 MUC2-6GalNAc +/-0.007 mM, pH7.4 Homo sapiens
0.066
-
 MUC2-6GalNAc +/-0.010 mM, mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
0.12
-
 IgA hinge-4GalNAc +/-0.01 mM, pH7.4 Homo sapiens
0.15
-
 MUC1 +/-0.03 mM, mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
0.25
-
 Muc2 +/-0.006 mM, mutant GalNAc-T2-D458H, pH7.4 Homo sapiens
0.26
-
 MUC1 +/-0.16 mM, pH7.4 Homo sapiens
0.32
-
 IgA hinge-4GalNAc +/-0.09 mM, mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
0.36
-
 MUC1 +/-0.19mM, mutant GalNAc-T2-D458H, pH7.4 Homo sapiens
0.81
-
 IgA hinge-4GalNAc +/-0.2 mM, mutant GalNAc-T2-D458H, pH7.4 Homo sapiens
0.86
-
 MUC1-2GalNAc +/-0.21 mM, mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
0.87
-
 MUC1-2GalNAc +/-0.23 mM, pH7.4 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
intracellular CHO ldlD-MUC1 cells in presence of GalNAc Homo sapiens 5622
-
intracellular CHO ldlD-MUC1 cells in presence of GalNAc: same pattern of biotinylated GalNAc-T2 like Tn (GalNAc-alpha-Ser/Thr) Homo sapiens 5622
-
intracellular CHO ldlD-MUC1 cells in presence of GalNAc: same pattern of biotinylated GalNAc-T4 and -T4 lectin like Tn (GalNAc-alpha-Ser/Thr) Homo sapiens 5622
-
intracellular human salivary glands Homo sapiens 5622
-
intracellular human salivary glands: same pattern of biotinylated GalNAc-T2 at Golgi-like supranuclear locations like Tn (GalNAc-alpha-Ser/Thr) Homo sapiens 5622
-
intracellular human salivary glands: same pattern of biotinylated GalNAc-T4 lectin at Golgi-like supranuclear locations like Tn (GalNAc-alpha-Ser/Thr) Homo sapiens 5622
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-N-acetyl-D-galactosamine + polypeptide Homo sapiens mucin-type O-linked glycosylation of serine or threonine residues UDP + N-acetyl-D-galactosaminyl-polypeptide
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q10471 GalNAc-T2
-
Homo sapiens Q10472 GalNAc-T1
-
Homo sapiens Q8N4A0 GalNAc-T4
-
Homo sapiens Q8NCW6 GalNAc-T11
-

Purification (Commentary)

Purification (Comment) Organism
purification of His-tagged truncated lectin domain by IMAC, 250 mM imidazole Homo sapiens
purification of secreted recombinant proteins from cell culture supernatant by Amberlite IRA-95 chromatography followed by SP Sepharose Fast Flow ion-exchange chromatography and concentrated by centrifugation through 10000 Da cut-off filter followed by elution from a PC3.2/3 column Homo sapiens

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 0.005 +/-0.007 micromol/min/ml, MUC1-2GalNaC by mutant GalNAc-T2-D458H, pH7.4 Homo sapiens
additional information
-
 0.018 +/-0.003 micromol/min/ml, MUC7, pH7.4 Homo sapiens
additional information
-
 0.018 +/-0.004 micromol/min/ml, MUC1-b’, pH7.4 Homo sapiens
additional information
-
 0.025 +/-0.008 micromol/min/ml, MUC1-2GalNAC, pH7.4 Homo sapiens
additional information
-
 0.028 +/-0.011 micromol/min/ml, MUC1-a' by mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
additional information
-
 0.029 +/-0.007 micromol/min/ml, MUC1-a' by mutant GalNAc-T2-D458H, pH7.4 Homo sapiens
additional information
-
 0.029 +/-0.008 micromol/min/ml, MUC7, pH7.4 Homo sapiens
additional information
-
 0.031 +/-0.003 micromol/min/ml, MUC1-a', pH7.4 Homo sapiens
additional information
-
 0.036 +/-0.003 micromol/min/ml, MUC7, pH7.4 Homo sapiens
additional information
-
 0.039 +/-0.010 micromol/min/ml, erythropoitin T, pH7.4 Homo sapiens
additional information
-
 0.046 +/-0.005 micromol/min/ml, MUC7 by mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
additional information
-
 0.046 +/-0.006 micromol/min/ml, MUC1-2GalNAC, pH7.4 Homo sapiens
additional information
-
 0.046 +/-0.009 micromol/min/ml, MUC2-6GalNAc by mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
additional information
-
 0.047 +/-0.011 micromol/min/ml, erythropoitin T by mutant GalNAc-T2-D458H, pH7.4 Homo sapiens
additional information
-
 0.051 +/-0.006 micromol/min/ml, hCG-beta, pH7.4 Homo sapiens
additional information
-
 0.053 +/-0.010 micromol/min/ml, MUC7 by mutant GalNAc-T2-D458H, pH7.4 Homo sapiens
additional information
-
 0.054 +/-0.001 micromol/min/ml, hCG-beta by mutant GalNAc-T2-D458H, pH7.4 Homo sapiens
additional information
-
 0.055 +/-0.008 micromol/min/ml, MUC1-2GalNaC by mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
additional information
-
 0.062 +/-0.010 micromol/min/ml, MUC2-6GalNAc, pH7.4 Homo sapiens
additional information
-
 0.065 +/-0.007 micromol/min/ml, hCG-beta by mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
additional information
-
 0.066 +/-0.008 micromol/min/ml, erythropoitin T by mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
additional information
-
 0.074 +/-0.005 micromol/min/ml, erythropoitin T, pH7.4 Homo sapiens
additional information
-
 0.076 +/-0.003 micromol/min/ml, erythropoitin T, pH7.4 Homo sapiens
additional information
-
 0.085 +/-0.003 micromol/min/ml, MUC1-a’, pH7.4 Homo sapiens
additional information
-
 0.086 +/-0.007 micromol/min/ml, MUC1-a’, pH7.4 Homo sapiens
additional information
-
 0.087 +/-0.006 micromol/min/ml, MUC1-b', pH7.4 Homo sapiens
additional information
-
 0.094 +/-0.008 micromol/min/ml, MUC1-b' by mutant GalNAc-T2-D458H, pH7.4 Homo sapiens
additional information
-
 0.097 +/-0.002 micromol/min/ml, MUC1, pH7.4 Homo sapiens
additional information
-
 0.108 +/-0.002 micromol/min/ml, OSM fragment, pH7.4 Homo sapiens
additional information
-
 0.121 +/-0.013 micromol/min/ml, MUC1 by mutant GalNAc-T2-D458H, pH7.4 Homo sapiens
additional information
-
 0.122 +/-0.007 micromol/min/ml, MUC1, pH7.4 Homo sapiens
additional information
-
 0.125 +/-0.003 micromol/min/ml, MUC2, pH7.4 Homo sapiens
additional information
-
 0.142 +/-0.005 micromol/min/ml, IgA hinge by mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
additional information
-
 0.151 +/-0.012 micromol/min/ml, MUC1 by mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
additional information
-
 0.158 +/-0.010 micromol/min/ml, MUC1, pH7.4 Homo sapiens
additional information
-
 0.161 +/-0.005 micromol/min/ml, IgA hinge, pH7.4 Homo sapiens
additional information
-
 0.164 +/-0.007 micromol/min/ml, MUC2 by mutant GalNAc-T2-D458H, pH7.4 Homo sapiens
additional information
-
 0.165 +/-0.013 micromol/min/ml, MUC2 by mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
additional information
-
 0.185 +/-0.006 micromol/min/ml, IgA hinge by mutant GalNAc-T2-D458H, pH7.4 Homo sapiens
additional information
-
 0.224 +/-0.002 micromol/min/ml, IgA hinge, pH7.4 Homo sapiens
additional information
-
 0.281 +/-0.013 micromol/min/ml, IgA hinge, pH7.4 Homo sapiens
additional information
-
 0.283 +/-0.010 micromol/min/ml, MUC2, pH7.4 Homo sapiens
additional information
-
 128 +/-0.007 micromol/min/ml, MUC1-b' by mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
additional information
-
 152 +/-0.018 micromol/min/ml, MUC2, pH7.4 Homo sapiens
45
-
 +/-13, UDP-GalNAc by mutant GalNAc-T2-D458H, pH7.4 Homo sapiens
46
-
 +/-12, UDP-GalNAc by mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
49
-
 +/-5, IgA hinge-4GalNAc by mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
56
-
 +/-6, UDP-Gal, pH7.4 Homo sapiens
65
-
 +/-5, UDP-Gal by mutant GalNAc-T2-D458H, pH7.4 Homo sapiens
69
-
 +/-12, UDP-GalNAc, pH7.4 Homo sapiens
72
-
 +/-21, MUC1-2GalNAc, pH7.4 Homo sapiens
81
-
 +/-1, MUC2, pH7.4 Homo sapiens
83
-
 +/-13, IgA hinge-4GalNAc, pH7.4 Homo sapiens
85
-
 +/-5, UDP-Gal by mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
94
-
 +/-5, MUC1 by mutant GalNAc-T2-D458H, pH7.4 Homo sapiens
97
-
 +/-14, MUC1, pH7.4 Homo sapiens
118
-
 +/-39, MUC1-2GalNAc by mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
119
-
 +/-24, IgA hinge-4GalNAc by mutant GalNAc-T2-D458H, pH7.4 Homo sapiens
143
-
 +/-15, MUC1 by mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
145
-
 +/-21, IgA hinge by mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
150
-
 +/-6, MUC2 by mutant GalNAc-T2-D458H, pH7.4 Homo sapiens
236
-
 +/-1, IgA hinge by mutant GalNAc-T2-D458H, pH7.4 Homo sapiens
273
-
 +/-12, MUC2 by mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
292
-
 +/-18, MUC2-6GalNAc by mutant GalNAc-T2-D541A, pH7.4 Homo sapiens
302
-
 +/-17, MUC2-6GalNAc, pH7.4 Homo sapiens
321
-
 +/-18, IgA hinge, pH7.4 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
erythropoietin T + UDP-Gal
-
 Homo sapiens erythropoietin T-nGalNAc + UDP
-
 ?
erythropoietin T + UDP-Gal also catalysed by mutants GalTNAc-T2-D458H and GalTNAc-T2-D541A Homo sapiens erythropoietin T-nGalNAc + UDP
-
 ?
hCG-beta + UDP-Gal
-
 Homo sapiens hCG-beta-nGalNAc + UDP
-
 ?
IgA hinge + UDP-Gal
-
 Homo sapiens IgA hinge-nGal + UDP
-
 ?
IgA hinge + UDP-GalNAc
-
 Homo sapiens IgA hinge-nGalNAc + UDP
-
 ?
IgA hinge + UDP-GalNAc GalTNAc-T11 incorporates only two GalNAc residues into IgA hinge peptide Homo sapiens IgA hinge-nGalNAc + UDP
-
 ?
IgA hinge + UDP-GalNAc mutant GalNAc-T2-D458H incorporates 1-2 fewer GalNAc residues than wild-type Homo sapiens IgA hinge-nGalNAc + UDP
-
 ?
IgA hinge-4GalNAc + UDP-GalNAc
-
 Homo sapiens IgA hinge-nGalNAc + UDP
-
 ?
additional information MUC1-2GalNAc, MUC2-6GalNAc, OSM fragments, hCG-beta are not substrates for GalNAc-T11 Homo sapiens ?
-
 ?
additional information MUC1b' and hCG-beta are no substrates for GalNAc-T1 Homo sapiens ?
-
 ?
MUC1 + UDP-GalNAc
-
 Homo sapiens MUC1-nGalNAc + UDP
-
 ?
MUC1 + UDP-GalNAc GalNAc-T4 lectin domain does not exhibit selective specificities for peptide sequences, or the density or pattern of GalNAc glycosylation, GalNAc-T4 lectin domain mediates GalNAc-glycopeptide substrate specificity Homo sapiens MUC1-nGalNAc + UDP
-
 ?
MUC1 + UDP-GalNAc mutant GalNAc-T2-D458H incorporates 1-2 fewer GalNAc residues than wild-type, GalNAc-T2 lectin domain does not exhibit selective specificities for peptide sequences, or the density or pattern of GalNAc glycosylation Homo sapiens MUC1-nGalNAc + UDP
-
 ?
MUC1-2GalNAc + UDP-GalNAc
-
 Homo sapiens MUC1-nGalNAc + UDP
-
 ?
MUC1a' + UDP-GalNAc
-
 Homo sapiens MUC1a'-nGalNAc + UDP
-
 ?
MUC1b' + UDP-GalNAc
-
 Homo sapiens MUC1b'-nGalNAc + UDP
-
 ?
MUC2 + UDP-GalNAc
-
 Homo sapiens MUC2-nGalNAc + UDP
-
 ?
MUC2-6GalNAc + UDP-GalNAc
-
 Homo sapiens MUC2-nGalNAc + UDP
-
 ?
MUC7 + UDP-GalNAc
-
 Homo sapiens MUC7-nGalNAc + UDP
-
 ?
OSM fragment + UDP-Gal
-
 Homo sapiens OSM fragment-nGalNAc + UDP
-
 ?
UDP-N-acetyl-D-galactosamine + polypeptide mucin-type O-linked glycosylation of serine or threonine residues Homo sapiens UDP + N-acetyl-D-galactosaminyl-polypeptide
-
 ?

Synonyms

Synonyms Comment Organism
(UDP)-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase
-
 Homo sapiens
GalNAc transferase
-
 Homo sapiens
GalNAc-T
-
 Homo sapiens
UDP GalNAc:polypeptide N-acetylgalactosaminyltransferase
-
 Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
additional information
-
 EDTA exhibits IC50 higher than 10 in all cases Homo sapiens additional information
additional information
-
 EDTA exhibits IC50s higher than 10 in all cases Homo sapiens additional information
additional information
-
 galactose and methyl-alpha/beta-Gal exhibit IC50 higher than 100 mM for GalNAc-T2 enzyme and lectin domain Homo sapiens additional information
additional information
-
 galactose and methyl-alpha/beta-Gal exhibit IC50s higher than 100 mM for GalNAc-T4 lectin domain Homo sapiens additional information
additional information
-
 GalNAc-T2 lectin domain exhibits no specificity for anomeric configuration of GalNAc according to simlar IC50s Homo sapiens additional information
additional information
-
 GalNAc-T4 lectin domain exhibits no specificity for anomeric configuration of GalNAc according to simlar IC50s Homo sapiens additional information
additional information
-
 glucose derivatives, lactose and UDP exhibit IC50 higher than 100 mM in all cases Homo sapiens additional information
additional information
-
 glucose derivatives, lactose and UDP exhibit IC50s higher than 100 mM in all cases Homo sapiens additional information
additional information
-
 UDP exhibits similar inhibitory effects on GalNAc-T2 and mutant GalNAc-T2-D458H Homo sapiens additional information
additional information
-
 UDP-alpha-GalNAc exhibits IC50 higher than 100 mM for GalNAc-T2 lectin domain Homo sapiens additional information
0.5
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T4 Homo sapiens o-nitrophenyl-alpha-GalNAc
0.8
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T4 Homo sapiens p-nitrophenyl-beta-GalNAc
1
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T4 Homo sapiens GalNAc
1
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T4 Homo sapiens benzyl-alpha-GalNAc
1
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T4 Homo sapiens phenyl-alpha-GalNAc
1
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T4 Homo sapiens o-nitrophenyl-beta-GalNAc
1
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T4 Homo sapiens p-nitrophenyl-alpha-GalNAc
5
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T2 Homo sapiens phenyl-alpha-GalNAc
5
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T4 lectin domain Homo sapiens GalNAc
5
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T4 lectin domain Homo sapiens benzyl-alpha-GalNAc
5
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T4 lectin domain Homo sapiens phenyl-alpha-GalNAc
5
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T4 lectin domain Homo sapiens o-nitrophenyl-alpha-GalNAc
7
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T2 Homo sapiens o-nitrophenyl-alpha-GalNAc
8
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T4 lectin domain Homo sapiens p-nitrophenyl-beta-GalNAc
8
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T4 lectin domain Homo sapiens ortho-nitrophenyl-beta-GalNAc
10
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T2 Homo sapiens p-nitrophenyl-beta-GalNAc
10
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T2 Homo sapiens o-nitrophenyl-beta-GalNAc
10
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T2 Homo sapiens p-nitrophenyl-alpha-GalNAc
10
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T2 lectin domain Homo sapiens p-nitrophenyl-beta-GalNAc
10
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T2 lectin domain Homo sapiens p-nitrophenyl-alpha-GalNAc
10
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T4 lectin domain Homo sapiens para-nitrophenyl-alpha-GalNAc
12
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T2 lectin domain Homo sapiens o-nitrophenyl-alpha-GalNAc
12
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T2 lectin domain Homo sapiens o-nitrophenyl-beta-GalNAc
15
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T2 Homo sapiens GalNAc
15
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T2 Homo sapiens benzyl-alpha-GalNAc
15
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T2 lectin domain Homo sapiens phenyl-alpha-GalNAc
20
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T2 lectin domain Homo sapiens benzyl-alpha-GalNAc
30
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T4 Homo sapiens UDP-alpha-GalNAc
37
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T2 lectin domain Homo sapiens GalNAc
40
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T4 Homo sapiens methyl-beta-Gal
50
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T4 Homo sapiens D-galactose
50
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T4 Homo sapiens methyl-alpha-Gal
50
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T4 lectin domain Homo sapiens UDP-alpha-GalNAc
65
-
 GalNAc-MUC1 binding to biotinylated GalNAc-T2 Homo sapiens UDP-alpha-GalNAc