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Literature summary for 2.4.1.38 extracted from

  • Tang, W.; Weng, S.; Zhang, S.; Wu, W.; Dong, L.; Shen, X.; Zhang, S.; Gu, J.; Xue, R.
    Direct interaction between surface beta1,4-galactosyltransferase 1 and epidermal growth factor receptor (EGFR) inhibits EGFR activation in hepatocellular carcinoma (2013), Biochem. Biophys. Res. Commun., 434, 449-454.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli DH5alpha cells Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
70000
-
x * 70000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-alpha-D-galactose + N-acetyl-beta-D-glucosaminylglycopeptide Homo sapiens
-
UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
GST Sepharose column chromatography, and gel filtration Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
SMMC-7721 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-alpha-D-galactose + N-acetyl-beta-D-glucosaminylglycopeptide
-
Homo sapiens UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide
-
?

Subunits

Subunits Comment Organism
? x * 70000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
beta1,4-galactosyltransferase 1
-
Homo sapiens
beta1,4GT1
-
Homo sapiens

General Information

General Information Comment Organism
physiological function direct interaction between the enzyme and epidermal growth factor receptor inhibits epidermal growth factor receptor activation in hepatocellular carcinoma Homo sapiens