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Literature summary for 2.4.1.37 extracted from

  • Betteridge, A.; Watkins, W.M.
    Two alpha-3-D-galactosyltransferases in rabbit stomach mucosa with different acceptor substrate specificities (1983), Eur. J. Biochem., 132, 29-35.
    View publication on PubMed
Search for more literature for 2.4.1.37

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.036
-
 UDP-galactose in reaction with 2'-fucosyllactose Oryctolagus cuniculus
0.05
-
 UDP-galactose in reaction with N-acetyllactosamine Oryctolagus cuniculus
0.08
-
 2'-fucosyllactose
-
 Oryctolagus cuniculus
0.8
-
 N-acetyllactosamine
-
 Oryctolagus cuniculus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane the enzyme catalyzing the transfer of galactose to 2'-fucosyllactose is much more tightly attached to membrane than the transferase which utilizes N-acetyllactosamine Oryctolagus cuniculus 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ divalent cation required, Mn2+ most effective, optimum concentration 20 mM Oryctolagus cuniculus

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
 2 distinct alpha-3-D-galactosyltransferases: one which is more tightly membrane-bound, resembles the human B-gene-specific transferase in its acceptor specificity, and the second, which is a more soluble enzyme transfers D-galactose to the same positional linkage in unsubstituted beta-D-galactosyl residues
-

Source Tissue

Source Tissue Comment Organism Textmining
stomach mucosa Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information 2 distinct alpha-3-D-galactosyltransferases: one which is more tightly membrane-bound, resembles the human B-gene-specific transferase in its acceptor specificity, and the second, which is a more soluble enzyme transfers D-galactose to the same positional linkage in unsubstituted beta-D-galactosyl residues Oryctolagus cuniculus ?
-
 ?
UDP-galactose + 2'-fucosyllactose
-
 Oryctolagus cuniculus UDP + alpha-D-galactosyl-1,3-[2'-fucosyllactose]
-
 ?
UDP-galactose + glycoprotein alpha-L-fucosyl-1,2-D-galactose
-
 Oryctolagus cuniculus UDP + glycoprotein alpha-D-galactosyl-1,3-[alpha-L-fucosyl-1,2]-D-galactose
-
 ?
UDP-galactose + N-acetyllactosamine
-
 Oryctolagus cuniculus UDP + alpha-D-galactosyl-1,3-[N-acetyl-lactosamine]
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.4 6.8 in reaction with N-acetyllactosamine Oryctolagus cuniculus
6.8
-
 in reaction with 2'-fucosyllactose Oryctolagus cuniculus