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Literature summary for 2.4.1.37 extracted from

  • Seto, N.O.L.; Palcic, M.M.; Hindsgaul, O.; Bundle, D.R.; Narang, S.A.
    Expression of a recombinant human glycosyltransferase from a synthetic gene and its utilization for synthesis of the human blood group B trisaccharide (1995), Eur. J. Biochem., 234, 323-328.
    View publication on PubMed
Search for more literature for 2.4.1.37

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli TG-1, the membrane-anchoring domain is replaced with an ompA bacterial secretory signal Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
octyl 3'-amino-3'-deoxy-alpha-L-fucopyranosyl-(1-2)-beta-D-galactopyranoside
-
 Homo sapiens
octyl 3'-deoxy-alpha-L-fucopyranosyl-(1-2)-beta-D-galactopyranoside
-
 Homo sapiens
octyl alpha-L-fucopyranosyl-(1-2)-beta-D-gulopyranoside
-
 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.06
-
 UDP-galactose
-
 Homo sapiens
0.099
-
 L-fucosyl-alpha-1,2-beta-D-galactosyl-O(CH2)7CH3
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.36
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-galactose + octyl 6'-amino-6'-deoxy-alpha-L-fucopyranosyl-(1-2)-beta-D-galactopyranoside
-
 Homo sapiens UDP + alpha-D-galactosyl-1,3-[6'-amino-6'-deoxy-alpha-L-fucosyl-1,2]-beta-D-galactosyl-O(CH2)7CH3
-
 ?
UDP-galactose + octyl 6'-deoxy-alpha-L-fucopyranosyl-(1-2)-beta-D-galactopyranoside
-
 Homo sapiens UDP + alpha-D-galactosyl-1,3-[6'-deoxy-alpha-L-fucosyl-1,2]-beta-D-galactosyl-O(CH2)7CH3
-
 ?
UDP-galactose + octyl 6'-fluoro-6'-deoxy-alpha-L-fucopyranosyl-(1-2)-beta-D-galactopyranoside
-
 Homo sapiens UDP + alpha-D-galactosyl-1,3-[6'-fluoro-6'-deoxy-alpha-L-fucosyl-1,2]-beta-D-galactosyl-O(CH2)7CH3
-
 ?
UDP-galactose + octyl 6'-O-methyl-alpha-L-fucopyranosyl-(1-2)-beta-D-galactopyranoside
-
 Homo sapiens UDP + alpha-D-galactosyl-1,3-[6'-O-methyl-alpha-L-fucosyl-1,2]-beta-D-galactosyl-O(CH2)7CH3
-
 ?

Synonyms

Synonyms Comment Organism
GTB
-
 Homo sapiens

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0078
-
 octyl alpha-L-fucopyranosyl-(1-2)-beta-D-gulopyranoside native enzyme Homo sapiens
0.026
-
 octyl alpha-L-fucopyranosyl-(1-2)-beta-D-gulopyranoside recombinant enzyme Homo sapiens