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Literature summary for 2.4.1.34 extracted from

  • Okada, H.; Abe, M.; Asakawa-Minemura, M.; Hirata, A.; Qadota, H.; Morishita, K.; Ohnuki, S.; Nogami, S.; Ohya, Y.
    Multiple functional domains of the yeast 1,3-beta-glucan synthase subunit Fks1p revealed by quantitative phenotypic analysis of temperature-sensitive mutants (2010), Genetics, 184, 1013-1024.
    View publication on PubMedView publication on EuropePMC
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Protein Variants

Protein Variants Comment Organism
additional information isolation of ten different temperature-sensitive fks1 mutants after random mutagenesis, quantitative cell morphology and biochemical properties of fks1 mutants, the putative catalytic subunit of the enzyme, the mutants show altered cell wall components and defects in endocytosis, pleiotropic phenotypes, overview. Some fks-1 mutants show intragenic complementation between fks1 mutations, while others do not Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
-
 Saccharomyces cerevisiae 5886
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-glucose + [(1,3)-beta-D-glucosyl]n Saccharomyces cerevisiae
-
 UDP + [(1,3)-beta-D-glucosyl]n+1
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
 gene fks1 encoding the catalytic subunit of the enzyme
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-glucose + [(1,3)-beta-D-glucosyl]n
-
 Saccharomyces cerevisiae UDP + [(1,3)-beta-D-glucosyl]n+1
-
 ?

Synonyms

Synonyms Comment Organism
Fks1p
-
 Saccharomyces cerevisiae

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
20 37 assay at, wild-type and temperature-sensitive mutants Saccharomyces cerevisiae

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 assay at Saccharomyces cerevisiae

General Information

General Information Comment Organism
physiological function the plasma membrane-localized 1,3-beta-glucan synthase synthesize the main filamentous structural component of the cell wall of the yeast Saccharomyces cerevisiae 1,3-beta-glucan Saccharomyces cerevisiae