Inhibitors | Comment | Organism | Structure |
---|---|---|---|
HM-1 | HM-1 inhibits the growth of yeast cells by forming a pore at the growing tip of the daughter cell, resulting in the formation of a protruding structure and eventual cell death. | Candida albicans | |
HM-1 | HM-1 inhibits the growth of yeast cells by forming a pore at the growing tip of the daughter cell, resulting in the formation of a protruding structure and eventual cell death. | [Candida] glabrata | |
HM-1 | HM-1 inhibits the growth of yeast cells by forming a pore at the growing tip of the daughter cell, resulting in the formation of a protruding structure and eventual cell death. | Candida parapsilosis | |
HM-1 | HM-1 inhibits the growth of yeast cells by forming a pore at the growing tip of the daughter cell, resulting in the formation of a protruding structure and eventual cell death. | Candida tropicalis | |
HM-1 | HM-1 inhibits the growth of yeast cells by forming a pore at the growing tip of the daughter cell, resulting in the formation of a protruding structure and eventual cell death. | Saccharomyces cerevisiae | |
monomeric single-chain variable fragment (scFv) | All four scFvs (scFv-A1, scFv-A2, scFv-A3, scFv-A4) inhibit beta-1,3-glucan-synthase. Most cultured cells treated with scFvs (3h) have a pearlike structure with protruding materials, characteristic of pore formation and similar to the morphology change after treatment with HM-1. These clearly indicate that the scFvs appear to have the same effect as HM-1 on sensitive yeast cells. | Candida albicans | |
monomeric single-chain variable fragment (scFv) | All four scFvs (scFv-A1, scFv-A2, scFv-A3, scFv-A4) inhibit beta-1,3-glucan-synthase. Most cultured cells treated with scFvs (3h) have a pearlike structure with protruding materials, characteristic of pore formation and similar to the morphology change after treatment with HM-1. These clearly indicate that the scFvs appear to have the same effect as HM-1 on sensitive yeast cells. | [Candida] glabrata | |
monomeric single-chain variable fragment (scFv) | All four scFvs (scFv-A1, scFv-A2, scFv-A3, scFv-A4) inhibit beta-1,3-glucan-synthase. Most cultured cells treated with scFvs (3h) have a pearlike structure with protruding materials, characteristic of pore formation and similar to the morphology change after treatment with HM-1. These clearly indicate that the scFvs appear to have the same effect as HM-1 on sensitive yeast cells. | Candida parapsilosis | |
monomeric single-chain variable fragment (scFv) | All four scFvs (scFv-A1, scFv-A2, scFv-A3, scFv-A4) inhibit beta-1,3-glucan-synthase. Most cultured cells treated with scFvs (3h) have a pearlike structure with protruding materials, characteristic of pore formation and similar to the morphology change after treatment with HM-1. These clearly indicate that the scFvs appear to have the same effect as HM-1 on sensitive yeast cells. | Candida tropicalis | |
monomeric single-chain variable fragment (scFv) | All four scFvs (scFv-A1, scFv-A2, scFv-A3, scFv-A4) inhibit beta-1,3-glucan-synthase. Most cultured cells treated with scFvs (3h) have a pearlike structure with protruding materials, characteristic of pore formation and similar to the morphology change after treatment with HM-1. These clearly indicate that the scFvs appear to have the same effect as HM-1 on sensitive yeast cells. | Saccharomyces cerevisiae | |
additional information | Preincubation with nMAb-KT eliminate the inhibition of Candida growth by scFv antibodies, suggestig that the observed cytocidal effect of scFv antibodies is due to their structural resemblance to HM-1. | Candida albicans | |
additional information | Preincubation with nMAb-KT eliminate the inhibition of Candida growth by scFv antibodies, suggestig that the observed cytocidal effect of scFv antibodies is due to their structural resemblance to HM-1. | [Candida] glabrata | |
additional information | Preincubation with nMAb-KT eliminate the inhibition of Candida growth by scFv antibodies, suggestig that the observed cytocidal effect of scFv antibodies is due to their structural resemblance to HM-1. | Candida parapsilosis | |
additional information | Preincubation with nMAb-KT eliminate the inhibition of Candida growth by scFv antibodies, suggestig that the observed cytocidal effect of scFv antibodies is due to their structural resemblance to HM-1. | Candida tropicalis | |
additional information | Preincubation with nMAb-KT eliminate the inhibition of Candida growth by scFv antibodies, suggestig that the observed cytocidal effect of scFv antibodies is due to their structural resemblance to HM-1. | Saccharomyces cerevisiae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Candida albicans | - |
- |
- |
Candida parapsilosis | - |
- |
- |
Candida tropicalis | - |
- |
- |
Saccharomyces cerevisiae | - |
- |
- |
[Candida] glabrata | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
beta-1,3-glucan synthase | - |
Saccharomyces cerevisiae |
beta-1,3-glucan synthase | - |
Candida albicans |
beta-1,3-glucan synthase | - |
Candida tropicalis |
beta-1,3-glucan synthase | - |
Candida parapsilosis |
beta-1,3-glucan synthase | - |
[Candida] glabrata |