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Literature summary for 2.4.1.331 extracted from

  • Ramos, A.; Olano, C.; Brana, A.F.; Mendez, C.; Salas, J.A.
    Modulation of deoxysugar transfer by the elloramycin glycosyltransferase ElmGT through site-directed mutagenesis (2009), J. Bacteriol., 191, 2871-2875.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.1.331

Protein Variants

Protein Variants Comment Organism
L309A mutation in residue of the alpha/beta/alpha motif, results in 4fold increase in efficiency of L-olivose transfer to 8-demethyltetracenomycin C Streptomyces olivaceus
L309H mutation in residue of the alpha/beta/alpha motif, results in decreases in the efficiency of deoxysugar transfer to 8-demethyltetracenomycin C Streptomyces olivaceus
L309I mutation in residue of the alpha/beta/alpha motif, results in 2fold increase in efficiency of L-rhamnose transfer to 8-demethyltetracenomycin C Streptomyces olivaceus
L309M mutation in residue of the alpha/beta/alpha motif, results in decreases in the efficiency of deoxysugar transfer to 8-demethyltetracenomycin C Streptomyces olivaceus
L309Q mutation in residue of the alpha/beta/alpha motif, results in decreases in the efficiency of deoxysugar transfer to 8-demethyltetracenomycin C Streptomyces olivaceus
L309V mutation in residue of the alpha/beta/alpha motif, results in 6fold increase in efficiency of L-olivose transfer to 8-demethyltetracenomycin C Streptomyces olivaceus
L309Y mutation in residue of the alpha/beta/alpha motif, results in 2fold increase in efficiency of L-olivose transfer to 8-demethyltetracenomycin C Streptomyces olivaceus
N312Q mutation in residue of the alpha/beta/alpha motif, results in 2fold increase in efficiency of L-olivose transfer to 8-demethyltetracenomycin C Streptomyces olivaceus
N312S mutation in residue of the alpha/beta/alpha motif, results in 2fold increase in efficiency of L-olivose transfer to 8-demethyltetracenomycin C Streptomyces olivaceus
N312T mutation in residue of the alpha/beta/alpha motif, results in 3fold increase in efficiency of L-olivose transfer to 8-demethyltetracenomycin C Streptomyces olivaceus

Organism

Organism UniProt Comment Textmining
Streptomyces olivaceus Q9F2F9
-
-
Streptomyces olivaceus Tü2353 Q9F2F9
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NDP-D-olivose + 8-demethyltetracenomycin C
-
 Streptomyces olivaceus NDP + 8-demethyl-8-alpha-D-olivosyltetracenomycin C
-
 ?
NDP-D-olivose + 8-demethyltetracenomycin C
-
 Streptomyces olivaceus Tü2353 NDP + 8-demethyl-8-alpha-D-olivosyltetracenomycin C
-
 ?
NDP-L-boivinose + 8-demethyltetracenomycin C
-
 Streptomyces olivaceus NDP + 8-demethyl-8-alpha-D-boivinosyltetracenomycin C
-
 ?
NDP-L-boivinose + 8-demethyltetracenomycin C
-
 Streptomyces olivaceus Tü2353 NDP + 8-demethyl-8-alpha-D-boivinosyltetracenomycin C
-
 ?
NDP-L-digitoxose + 8-demethyltetracenomycin C
-
 Streptomyces olivaceus NDP + 8-demethyl-8-alpha-L-digitoxosyltetracenomycin C
-
 ?
NDP-L-digitoxose + 8-demethyltetracenomycin C
-
 Streptomyces olivaceus Tü2353 NDP + 8-demethyl-8-alpha-L-digitoxosyltetracenomycin C
-
 ?
NDP-L-olivose + 8-demethyltetracenomycin C
-
 Streptomyces olivaceus NDP + 8-demethyl-8-alpha-L-olivosylyltetracenomycin C
-
 ?
NDP-L-olivose + 8-demethyltetracenomycin C
-
 Streptomyces olivaceus Tü2353 NDP + 8-demethyl-8-alpha-L-olivosylyltetracenomycin C
-
 ?
NDP-L-rhamnose + 8-demethyltetracenomycin C
-
 Streptomyces olivaceus NDP + 8-demethyl-8-alpha-L-rhamnosyltetracenomycin C
-
 ?
NDP-L-rhamnose + 8-demethyltetracenomycin C
-
 Streptomyces olivaceus Tü2353 NDP + 8-demethyl-8-alpha-L-rhamnosyltetracenomycin C
-
 ?