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Literature summary for 2.4.1.324 extracted from

  • Bhat, W.W.; Dhar, N.; Razdan, S.; Rana, S.; Mehra, R.; Nargotra, A.; Dhar, R.S.; Ashraf, N.; Vishwakarma, R.; Lattoo, S.K.
    Molecular characterization of UGT94F2 and UGT86C4, two glycosyltransferases from Picrorhiza kurrooa: comparative structural insight and evaluation of substrate recognition (2013), PLoS ONE, 8, e73804.
    View publication on PubMedView publication on EuropePMC

Crystallization (Commentary)

Crystallization (Comment) Organism
molecular modeling and ligand docking studies. The enzyme shows maximum binding affinity towards 7-deoxyloganetin. Apigenin, kaempferol and naringenin show very poor binding affinity towards the protein’s acceptor site Picrorhiza kurrooa

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
55000
-
x * 55000, calculated Picrorhiza kurrooa

Organism

Organism UniProt Comment Textmining
Picrorhiza kurrooa L7QGZ9
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-alpha-D-glucose + 7-deoxyloganetin
-
Picrorhiza kurrooa UDP + 7-deoxyloganin
-
?

Subunits

Subunits Comment Organism
? x * 55000, calculated Picrorhiza kurrooa

Synonyms

Synonyms Comment Organism
UGT94F2
-
Picrorhiza kurrooa
uridine diphosphate glycosyltransferase
-
Picrorhiza kurrooa

pI Value

Organism Comment pI Value Maximum pI Value
Picrorhiza kurrooa calculated
-
5.3

Expression

Organism Comment Expression
Picrorhiza kurrooa expression is strongly induced by phytohormone treatments: 15fold increase in the expression after 24 h of methyl jasmonate application, 10fold after 12 h of treatment with salicylic acid up