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Literature summary for 2.4.1.277 extracted from

  • Kao, C.L.; Borisova, S.A.; Kim, H.J.; Liu, H.W.
    Linear aglycones are the substrates for glycosyltransferase DesVII in methymycin biosynthesis: analysis and implications (2006), J. Am. Chem. Soc., 128, 5606-5607.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Streptomyces venezuelae Q9ZGH7
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme can also recognize and process the linear precursor of its macrolactone substrate with reduced but measurable activity. The reaction is regioselective because only one singly glycosylated product is generated in each case despite the presence of multiple potential glycosylation sites. The substitution patterns nearby the glycosylation site, and not the ring conformation, are the major recognition determinants for glycosyltransferase Streptomyces venezuelae ?
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Synonyms

Synonyms Comment Organism
glycosyltransferase DesVII
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Streptomyces venezuelae