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Literature summary for 2.4.1.277 extracted from

  • Borisova, S.A.; Zhao, L.; Melancon III, C.E.; Kao, C.L.; Liu, H.W.
    Characterization of the glycosyltransferase activity of desVII: analysis of and implications for the biosynthesis of macrolide antibiotics (2004), J. Am. Chem. Soc., 126, 6534-6535.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
TDP-3-dimethylamino-4,6-dideoxy-alpha-D-glucopyranose + 10-deoxymethynolide Streptomyces venezuelae the enzyme is involved in biosynthesis of macrolide antibiotics dTDP + 10-deoxymethymycin
-
 ?
TDP-3-dimethylamino-4,6-dideoxy-alpha-D-glucopyranose + narbonolide Streptomyces venezuelae the enzyme is involved in biosynthesis of macrolide antibiotics dTDP + narbomycin
-
 ?

Organism

Organism UniProt Comment Textmining
Streptomyces venezuelae Q9ZGH7
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
TDP-3-dimethylamino-4,6-dideoxy-alpha-D-glucopyranose + 10-deoxymethynolide
-
 Streptomyces venezuelae dTDP + 10-deoxymethymycin
-
 ?
TDP-3-dimethylamino-4,6-dideoxy-alpha-D-glucopyranose + 10-deoxymethynolide the enzyme is involved in biosynthesis of macrolide antibiotics Streptomyces venezuelae dTDP + 10-deoxymethymycin
-
 ?
TDP-3-dimethylamino-4,6-dideoxy-alpha-D-glucopyranose + narbonolide
-
 Streptomyces venezuelae dTDP + narbomycin
-
 ?
TDP-3-dimethylamino-4,6-dideoxy-alpha-D-glucopyranose + narbonolide the enzyme is involved in biosynthesis of macrolide antibiotics Streptomyces venezuelae dTDP + narbomycin
-
 ?

Synonyms

Synonyms Comment Organism
DesVII
-
 Streptomyces venezuelae

General Information

General Information Comment Organism
physiological function the enzyme is involved in biosynthesis of macrolide antibiotics Streptomyces venezuelae