Protein Variants | Comment | Organism |
---|---|---|
additional information | alg3 mutant | Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Saccharomyces cerevisiae | involved in oligosaccharide-lipid synthesis | ? | - |
? | |
additional information | Saccharomyces cerevisiae A | involved in oligosaccharide-lipid synthesis | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | P38179 | - |
- |
Saccharomyces cerevisiae | P38179 | A | - |
Saccharomyces cerevisiae A | P38179 | A | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GDP-alpha-D-mannose + Manalpha(1-2)Manalpha(1-2)Manalpha(1-3)(Manalpha(1-6))Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-PP-dolichol | alg3 Man5GlcNAc2 precursor | Saccharomyces cerevisiae | GDP + Manalpha(1-2)Manalpha(1-2)Manalpha(1-3)(Manalpha(1-3)Manalpha(1-6))Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-PP-dolichol | - |
? | |
GDP-alpha-D-mannose + Manalpha(1-2)Manalpha(1-2)Manalpha(1-3)(Manalpha(1-6))Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-PP-dolichol | alg3 Man5GlcNAc2 precursor | Saccharomyces cerevisiae A | GDP + Manalpha(1-2)Manalpha(1-2)Manalpha(1-3)(Manalpha(1-3)Manalpha(1-6))Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-PP-dolichol | - |
? | |
additional information | involved in oligosaccharide-lipid synthesis | Saccharomyces cerevisiae | ? | - |
? | |
additional information | involved in oligosaccharide-lipid synthesis | Saccharomyces cerevisiae A | ? | - |
? |
General Information | Comment | Organism |
---|---|---|
malfunction | alg3 yeast accumulates Man5GlcNAc2-P-P-dolichol due to a defective alphal,3-mannosyltransferase required for the next step in oligosaccharide-lipid elongation | Saccharomyces cerevisiae |