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Literature summary for 2.4.1.255 extracted from

  • Liu, X.; Li, L.; Wang, Y.; Yan, H.; Ma, X.; Wang, P.G.; Zhang, L.
    A peptide panel investigation reveals the acceptor specificity of O-GlcNAc transferase (2014), FASEB J., 28, 3362-3372.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in HeLa cells Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
crystalline alpha + UDP-GlcNAc i.e. small heat-shock protein crystalline alpha Homo sapiens ? + UDP
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?
additional information modification occurs predominantly in a random coil region, with signature sequence, PPVS/TSATT, around the modification site (underlined, position 0). A substrate (peptide or protein) with Pro, Ala at position -2, and/or Val, Ala, Thr, Ser at position -1, and/or Ala, Ser, Pro, Thr, Gly at position +2 would have more chances for O-GlcNAcylation Homo sapiens ?
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?