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Literature summary for 2.4.1.255 extracted from

  • Zhang, F.; Snead, C.M.; Catravas, J.D.
    Hsp90 regulates O-linked beta-N-acetylglucosamine transferase: a novel mechanism of modulation of protein O-linked beta-N-acetylglucosamine modification in endothelial cells (2012), Am. J. Physiol. Cell Physiol., 302, C1786-C1796.
    View publication on PubMedView publication on EuropePMC

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
78000
-
2 * 110000 + 1 * 78000, SDS-PAGE Bos taurus
78000
-
2 * 110000 + 1 * 78000, SDS-PAGE Homo sapiens
110000
-
2 * 110000 + 1 * 78000, SDS-PAGE Bos taurus
110000
-
2 * 110000 + 1 * 78000, SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Homo sapiens O15294
-
-

Source Tissue

Source Tissue Comment Organism Textmining
arterial endothelial cell
-
Bos taurus
-
HLMVE cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information heat shock protein 90 (Hsp90) is involved in the regulation of O-linked beta-N-acetylglucosamine transferase. Inhibition of Hsp90 by radicicol or 17-N-allylamino-17-demethoxygeldanamycin destabilizes the enzyme and dramatically reduces its half-life in primary cultures of endothelial cells Bos taurus ?
-
?
additional information heat shock protein 90 (Hsp90) is involved in the regulation of O-linked beta-N-acetylglucosamine transferase. Inhibition of Hsp90 by radicicol or 17-N-allylamino-17-demethoxygeldanamycin destabilizes the enzyme and dramatically reduces its half-life in primary cultures of endothelial cells Homo sapiens ?
-
?

Subunits

Subunits Comment Organism
heterotrimer 2 * 110000 + 1 * 78000, SDS-PAGE Bos taurus
heterotrimer 2 * 110000 + 1 * 78000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
O-linked beta-N-acetylglucosamine transferase
-
Bos taurus
O-linked beta-N-acetylglucosamine transferase
-
Homo sapiens
OGT
-
Bos taurus
OGT
-
Homo sapiens