Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000025 | - |
Nup62 | - |
Homo sapiens | |
0.000227 | - |
Nup62 | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Homo sapiens | 5739 | - |
nucleocytoplasm | - |
Homo sapiens | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
78000 | - |
sOGT | Homo sapiens |
103000 | - |
mOGT | Homo sapiens |
116000 | - |
ncOGT | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | catalyzes the transfer of O-linked GlcNAc to serine or threonine residues of a variety of substrate proteins, including nuclear pore proteins, transcription factors, and proteins implicated in diabetes and neurodegenerative disorders | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | catalyzes the transfer of O-linked GlcNAc to serine or threonine residues of a variety of substrate proteins, including nuclear pore proteins, transcription factors, and proteins implicated in diabetes and neurodegenerative disorders | Homo sapiens | ? | - |
? | |
UDP-GlcNAc + Nup62 protein | - |
Homo sapiens | UDP + N-acetyl-D-glucosmainyl-[Nup62 protein] | - |
? | |
UDP-N-acetyl-alpha-D-glucosamine + [Nup62 protein]-L-serine | - |
Homo sapiens | UDP + [Nup62 protein]-3-O-(N-acetyl-beta-D-glucosaminyl)-L-serine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
mOGT | isoform | Homo sapiens |
More | the short isoform of OGT (sOGT) does not glycosylate any of the substrates tested, although it retains a potentially active catalytic domain | Homo sapiens |
ncOGT | isoform | Homo sapiens |
O-GlcNAc transferase | - |
Homo sapiens |
O-linked N-acetylglucosaminyltransferase | - |
Homo sapiens |
OGT | - |
Homo sapiens |
sOGT | isoform | Homo sapiens |