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Literature summary for 2.4.1.255 extracted from

  • Andrali, S.S.; Marz, P.; Ozcan, S.
    Ataxin-10 interacts with O-GlcNAc transferase OGT in pancreatic beta cells (2005), Biochem. Biophys. Res. Commun., 337, 149-153.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
Ataxin-10 encoded by the SCA10 (spinocerebellar ataxia type 10) gene, interacts with O-GlcNAc transferase OGT in pancreatic beta cells Homo sapiens
hyperglycemia increases O-GlcNAc levels in pancreatic beta cells, which appears to interfere with beta-cell function Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
the mitochondrial version of human OGT is subcloned into the pSos vector in-frame with the human Sos protein Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
pancreas
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
O-GlcNAc transferase
-
Homo sapiens
O-GlcNAc transferase OGT
-
Homo sapiens
O-linked N-acetylglucosamine transferase
-
Homo sapiens
OGT
-
Homo sapiens