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Literature summary for 2.4.1.232 extracted from

  • Izquierdo, L.; Mehlert, A.; Ferguson, M.A.
    The lipid-linked oligosaccharide donor specificities of Trypanosoma brucei oligosaccharyltransferases (2012), Glycobiology, 22, 696-703.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Trypanosoma brucei
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gene ALG12
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Synonyms

Synonyms Comment Organism
alpha1-6-mannosyltransferase
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Trypanosoma brucei
Dol-P-Man:Man7GlcNAc2-PP-Dol-alpha1-6-mannosyltransferase
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Trypanosoma brucei
TbALG12
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Trypanosoma brucei

General Information

General Information Comment Organism
malfunction the variant surface glycoprotein sVSG221 synthesized by the ALG12-/- parasites shows different glycosylation patterns to that synthesized by wild-type cells, changes in sVSG221 glycosylation induced by the deletion of the ALG12 gene, overview Trypanosoma brucei
physiological function the TbALG12 gene encodes the alpha1-6-mannosyltransferase that converts Man7GlcNAc2-PP-Dol to Man8GlcNAc2-PP-Dol Trypanosoma brucei