Cloned (Comment) | Organism |
---|---|
DV1, expression of soluble form of rib-2 protein in COS-1 cells | Caenorhabditis elegans |
expression of soluble form of EXT1 and EXT2 proteins in COS-1 cells | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
110000 | - |
expressed fusion protein from COS-1after N-glycosidase treatment, SDS-PAGE | Caenorhabditis elegans |
130000 | - |
expressed fusion protein from COS-1, SDS-PAGE | Caenorhabditis elegans |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan | Homo sapiens | elongation of growing chains of heparin and heparan sulfate, tumor suppressor | UDP + N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan | - |
? | |
UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan | Caenorhabditis elegans | elongation of growing chains of heparin and heparan sulfate, tumor suppressor | UDP + N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Caenorhabditis elegans | - |
- |
- |
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | N-linked glycosylation, molecular weight of expressed fusion protein is reduced from 1300000 to 110000 by N-glycosidase treatment | Caenorhabditis elegans |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | EXT1 and EXT2 proteins also acts as beta(1,4)-glucuronyltransferase (EC 2.4.1.225) | Homo sapiens | ? | - |
? | |
additional information | different acceptors tested for activity with UDP-N-acetyl-D-glucosamine | Homo sapiens | ? | - |
? | |
additional information | different acceptors tested for activity with UDP-N-acetyl-D-glucosamine | Caenorhabditis elegans | ? | - |
? | |
UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan | - |
Homo sapiens | UDP + N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan | - |
? | |
UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan | - |
Caenorhabditis elegans | UDP + N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan | - |
? | |
UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan | elongation of growing chains of heparin and heparan sulfate, tumor suppressor | Homo sapiens | UDP + N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan | - |
? | |
UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan | elongation of growing chains of heparin and heparan sulfate, tumor suppressor | Caenorhabditis elegans | UDP + N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan | - |
? |
Synonyms | Comment | Organism |
---|---|---|
More | - |
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