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Literature summary for 2.4.1.206 extracted from

  • Rossi, F.; Gornati, R.; Rizzo, A.M.; Venturini, L.; Bernadini, G.; Berra, B.
    Glycolipid glycosyltransferase activities during early development of Xenopus: effect of retinoic acid (1999), Cell Biol. Int., 23, 91-95.
    View publication on PubMed
Search for more literature for 2.4.1.206

Activating Compound

Activating Compound Comment Organism Structure
retinoic acid activates enzyme activity, leads to developmental malformations of the embryos Xenopus sp.
Triton CF-54
-
 Xenopus sp.

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+
-
 Xenopus sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-N-acetyl-D-glucosamine + lactosylceramide Xenopus sp. enzyme is active at the branching point of lactosylceramide metabolism, directs lactosylceramide into the glycolipids of the lacto-series UDP + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide
-
 ?
UDP-N-acetyl-D-glucosamine + lactosylceramide Xenopus sp. glycolipid biosynthesis UDP + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide
-
 ?

Organism

Organism UniProt Comment Textmining
Xenopus sp.
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Xenopus sp.
-
embryo
-
 Xenopus sp.
-
additional information retinoic acid activates the enzyme and leads to developmental malformations of the embryos, overview Xenopus sp.
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.00000065
-
 embryo Xenopus sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-N-acetyl-D-glucosamine + D-galactosyl-1,4-beta-D-glucosylceramide i.e. lactosylceramide Xenopus sp. UDP + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide
-
 ?
UDP-N-acetyl-D-glucosamine + lactosylceramide enzyme is active at the branching point of lactosylceramide metabolism, directs lactosylceramide into the glycolipids of the lacto-series Xenopus sp. UDP + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide
-
 ?
UDP-N-acetyl-D-glucosamine + lactosylceramide glycolipid biosynthesis Xenopus sp. UDP + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide
-
 ?

Synonyms

Synonyms Comment Organism
LacCer(beta1,3)N-acetylglucosaminyltransferase
-
 Xenopus sp.

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Xenopus sp.

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.6
-
 assay at Xenopus sp.