Cloned (Comment) | Organism |
---|---|
gene UGT2A1, recombinant expression of C-terminally His-tagged enzyme in Spodoptera frugiperda Sf9 cells via baculovirus transfection | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | Michaelis-Menten kinetic modeling, overview | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the human UGTs of subfamily 2A, UGT2A1, 2A2, and 2A3, show bile acid-conjugating activity | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Homo sapiens | Q6UWM9 | - |
- |
Homo sapiens | Q9Y4X1 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the human UGTs of subfamily 2A, UGT2A1, 2A2, and 2A3, show bile acid-conjugating activity | Homo sapiens | ? | - |
? | |
additional information | activity with all tested bile acids is high with isozyme UGT2A1 | Homo sapiens | ? | - |
? | |
additional information | activity with all tested bile acids is low with isozyme UGT2A3 | Homo sapiens | ? | - |
? | |
UDP-glucuronate + chenodeoxycholic acid | - |
Homo sapiens | UDP + chenodeoxycholic acid 24-beta-D-glucuronoside | - |
? | |
UDP-glucuronate + chenodeoxycholic acid | best substrate | Homo sapiens | UDP + chenodeoxycholic acid 24-beta-D-glucuronoside | - |
? | |
UDP-glucuronate + cholic acid | - |
Homo sapiens | UDP + cholic acid 24-beta-D-glucuronoside | - |
? | |
UDP-glucuronate + cholic acid | best substrate | Homo sapiens | UDP + cholic acid 24-beta-D-glucuronoside | - |
? | |
UDP-glucuronate + deoxycholic acid | - |
Homo sapiens | UDP + deoxycholic acid 24-beta-D-glucuronoside | - |
? | |
UDP-glucuronate + hyocholic acid | - |
Homo sapiens | UDP + hyocholic acid 24-beta-D-glucuronoside | - |
? | |
UDP-glucuronate + hyodeoxycholic acid | - |
Homo sapiens | UDP + hyodeoxycholic acid 24G-beta-D-glucuronoside | - |
? | |
UDP-glucuronate + lithocholic acid | - |
Homo sapiens | UDP + lithocholic acid 3-beta-D-glucuronoside + lithocholic acid 24-beta-D-glucuronoside | - |
? |
Synonyms | Comment | Organism |
---|---|---|
UDP-glucuronosyltransferase | - |
Homo sapiens |
UGT | - |
Homo sapiens |
UGT2A1 | - |
Homo sapiens |
UGT2A2 | - |
Homo sapiens |
UGT2A3 | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |