Cloned (Comment) | Organism |
---|---|
isoform UGT1A10, expression in insect cell | Homo sapiens |
isoform UGT1A6, expression in insect cell | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Homo sapiens | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
jejunum | isoform UGT1A10, preferential formation of 4-menadiol glucuronide | Homo sapiens | - |
liver | isoform UGT1A10 | Homo sapiens | - |
liver | isoform UGT1A6, preferential formation of 1-menadiol glucuronide | Homo sapiens | - |
additional information | no activity of isoform UGT1A6 in the jejunum | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-D-glucuronate + menadiol | - |
Homo sapiens | UDP + mendadiol 1-O-beta-D-glucuronoside | - |
? | |
UDP-D-glucuronate + menadiol | - |
Homo sapiens | UDP + mendadiol 1-O-beta-D-glucuronoside | isoform UGT1A6, formation of 1-menadiol glucuronide and 4-menadiol glucuronide in ratio of about 4:1 | ? | |
UDP-D-glucuronate + menadiol | - |
Homo sapiens | UDP + mendadiol 4-O-beta-D-glucuronoside | isoform UGT1A10, preferential formation of 4-menadiol glucuronoside | ? | |
UDP-D-glucuronate + menadiol | - |
Homo sapiens | UDP + mendadiol 4-O-beta-D-glucuronoside | isoform UGT1A6, formation of 1-menadiol glucuronide and 4-menadiol glucuronide in ratio of about 4:1 | ? |