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Literature summary for 2.4.1.17 extracted from
- Activation and inhibition of rat hepatic UDP-glucuronyltransferase by mercuric acetate (1981), Xenobiotica, 11, 97-102.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Hg2+ | inhibition of 4-methylumbelliferone UDP-glucuronyltransferase | Rattus norvegicus |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Rattus norvegicus | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Hg2+ | activation of bilirubin UDP-glucuronyltransferase | Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-methylumbelliferone + UDP-glucuronate | - |
Rattus norvegicus | UDP + 4-methylumbelliferyl-7-O-beta-D-glucuronide | - |
? | |
| bilirubin + UDPglucuronate | not inducible by phenobarbital, methylcholanthrene, 2,3,7,8-tetrachlorodibenzo-p-dioxin | Rattus norvegicus | bilirubin monoglucuronoside + bilirubin diglucuronoside + UDP | - |
? | |
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