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Literature summary for 2.4.1.16 extracted from

  • Schmidt, M.; Drgon, T.; Bowers, B.; Cabib, E.
    Hyperpolarized growth of Saccharomyces cerevisiae cak1P212S and cla4 mutants weakens cell walls and renders cells dependent on chitin synthase 3 (2008), FEMS Yeast Res., 8, 362-373.
    View publication on PubMed
Search for more literature for 2.4.1.16

Application

Application Comment Organism
analysis the chs3 gene encoding the chitin synthase 3 is used for synthetically lethality screening for mutation determination, overview Saccharomyces cerevisiae

Protein Variants

Protein Variants Comment Organism
additional information screening for mutations synthetically lethal with chs3 in the indicator strain ECY46-4-1B, the thin cell wall phenotype is caused by a mutation of the Cdc28-activating kinase CAK1 gene, phenotype, reduced or increased CSIII activity, overview Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Saccharomyces cerevisiae 16020
-

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P29465 gene chs3coding for the catalytic subunit of the chitin synthase III
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-GlcNAc + GlcNAc
-
 Saccharomyces cerevisiae UDP + N-acetyl-beta-D-glucosaminyl-(1,4)-N-acetyl-beta-D-glucosamine
-
 ?

Synonyms

Synonyms Comment Organism
chitin synthase 3
-
 Saccharomyces cerevisiae
chitin synthase III
-
 Saccharomyces cerevisiae
CSIII
-
 Saccharomyces cerevisiae

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Saccharomyces cerevisiae

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 assay at Saccharomyces cerevisiae