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Literature summary for 2.4.1.16 extracted from

  • Ryder, N.S.; Peberdy, J.F.
    Chitin synthase in Aspergillus nidulans: properties and proteolytic activation (1977), J. Gen. Microbiol., 99, 69-76.
No PubMed abstract available
Search for more literature for 2.4.1.16

Inhibitors

Inhibitors Comment Organism Structure
EDTA 10 mM, complete inhibition Aspergillus nidulans

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.2
-
 UDP-GlcNAc
-
 Aspergillus nidulans
3.1
-
 UDP-N-acetylglucosamine
-
 Aspergillus nidulans

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Aspergillus nidulans 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ greatly stimulated by Mg2+, optimal concentration is 2.5 mM, half-maximal activity at 17 mM Aspergillus nidulans

Organism

Organism UniProt Comment Textmining
Aspergillus nidulans
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification activity can be increased 6fold by digestion of the enzyme preparation with trypsin Aspergillus nidulans

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-N-acetyl-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n
-
 Aspergillus nidulans UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30.5
-
-
 Aspergillus nidulans

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
17.5 41 50% of maximal activity at 17.5°C and at 41°C Aspergillus nidulans

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
 Aspergillus nidulans

pH Range

pH Minimum pH Maximum Comment Organism
7.1 8.3 50% of maximal activity at pH 7.1 and pH 8.3 Aspergillus nidulans