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Literature summary for 2.4.1.155 extracted from

  • Kim, Y.S.; Hwang, S.Y.; Kang, H.Y.; Sohn, H.; Oh, S.; Kim, J.Y.; Yoo, J.S.; Kim, Y.H.; Kim, C.H.; Jeon, J.H.; Lee, J.M.; Kang, H.A.; Miyoshi, E.; Taniguchi, N.; Yoo, H.S.; Ko, J.H.
    Functional proteomics study reveals that N-acetylglucosaminyltransferase V reinforces the invasive/metastatic potential of colon cancer through aberrant glycosylation on tissue inhibitor of metalloproteinase-1 (2008), Mol. Cell. Proteomics, 7, 1-14.
    View publication on PubMed

Application

Application Comment Organism
medicine knowledge of the biological behavior of metalloproteinases and tissue inhibitor of metalloproteinases and the roles in various diseases have an eventual goal of therapeutic uses and clinical trials of anti-cancer agents Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
a recombinant vector MGAT5-pCXNneo is constructed for transfection of WiDr cells Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-N-acetyl-D-glucosamine + 6-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R Homo sapiens
-
UDP + 6-(2,6-bis[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
WiDr cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-1-antitrypsin precursor + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
angiotensinogen preproprotein + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
beta-N-acetylhexosaminidase A + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
cathepsin D preproprotein + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
cathepsin X precursor + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
DDR1 variant protein + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
dipeptidyl peptidase 7 preproprotein + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
discoidin receptor tyrosine kinase + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
dystroglycan 1 precursor + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
galectin 3 binding protein + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
granulin isoform 1 precursor + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
heat shock protein 70 kDa protein 8 isoform 1 + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
heat shock protein gp96 precursor + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
heparan sulfate proteoglycan perlecan + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
hexosaminidase B preproprotein + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
human Fc binding protein + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
Ig kappa chain V-III + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
laminin gamma1 precursor + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
legumain preproprotein + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
met proto-oncogene + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
N-acetylgalactosamine-6-sulfatase + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
N-acetylglucosamine-6-sulfatase + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
prosaposin + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
protective protein for beta-galactosidase + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
protein tyrosine phosphatase kappa + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
protein-tyrosine kinase-related receptor PTK7 + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
ribonuclease T2 precursor + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
tissue inhibitor of metalloproteinase-1 + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
tumor-associated calcium signal transducer 1 + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?
UDP-N-acetyl-D-glucosamine + 6-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R
-
Homo sapiens UDP + 6-(2,6-bis[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R
-
?
Zn-alpha-2-glycoprotein + UDP-N-acetyl-D-glucosamine identified target protein for GnT-V in human colon cancer cell WiDr Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
GnT-V
-
Homo sapiens
N-acetylglucosaminyltransferase V
-
Homo sapiens