Literature summary for 2.4.1.152 extracted from

Holmes, E.H.; Yen, T.Y.; Thomas, S.; Joshi, R.; Nguyen, A.; Long, T.; Gallet, F.; Maftah, A.; Julien, R.; Macher, B.A.
Human alpha1,3/4 fucosyltransferases. Characterization of highly conserved cysteine residues and N-linked glycosylation sites (2000), J. Biol. Chem., 275, 24237-24245.

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Protein Variants

Protein Variants	Comment	Organism
C104S	mutant enzyme is inactive, mutant enzyme produces a series of lower molecular weight bands when characterized by Wester blot and does not bind GDP	Homo sapiens
C351S	mutant enzyme is inactive	Homo sapiens
C354S	mutant enzyme is inactive	Homo sapiens
C94S	mutant enzyme is inactive	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
GDP-hexanolamine	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

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Release 2023.1 (January 2023)