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Literature summary for 2.4.1.15 extracted from

  • Vandercammen, A.; Francois, J.; Hers, H.G.
    Characterization of trehalose-6-phosphate synthase and trehalose-6-phosphate phosphatase of Saccharomyces cerevisiae (1989), Eur. J. Biochem., 182, 613-620.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Mg2+ inhibition in presence of 1 mM UDP or 1 mM UTP Saccharomyces cerevisiae
phosphate noncompetitive with respect to noth UDPglucose or glucose 6-phosphate; potent noncompetitive inhibitor Saccharomyces cerevisiae

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
additional information
-
Saccharomyces cerevisiae
0.5
-
UDPglucose
-
Saccharomyces cerevisiae
3.5
-
glucose 6-phosphate
-
Saccharomyces cerevisiae

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ 2fold stimulation at 5 mM Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDPglucose + glucose 6-phosphate
-
Saccharomyces cerevisiae trehalose 6-phosphate + UDP
-
?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2
-
phosphate
-
Saccharomyces cerevisiae