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Literature summary for 2.4.1.148 extracted from

  • Suzuki, Y.; Sutoh, M.; Hatakeyama, S.; Mori, K.; Yamamoto, H.; Koie, T.; Saitoh, H.; Yamaya, K.; Funyu, T.; Habuchi, T.; Arai, Y.; Fukuda, M.; Ohyama, C.; Tsuboi, S.
    MUC1 carrying core 2 O-glycans functions as a molecular shield against NK cell attack, promoting bladder tumor metastasis (2012), Int. J. Oncol., 40, 1831-1838.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine the expression of the enzyme in bladder tumors positively correlates with tumor progression Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
bladder cancer cell
-
Homo sapiens
-
KK-47 cell
-
Homo sapiens
-
YTS-1 cell
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
C2GnT
-
Homo sapiens
core 2 beta-1,6-N-acetylglucosaminyltransferase
-
Homo sapiens

General Information

General Information Comment Organism
physiological function enzyme expressing tumor are more resistant to natural killer cell cytotoxicity than tumor cells with reduced enzyme expression Homo sapiens