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Literature summary for 2.4.1.148 extracted from

  • Ismail, M.N.; Stone, E.L.; Panico, M.; Lee, S.H.; Luu, Y.; Ramirez, K.; Ho, S.B.; Fukuda, M.; Marth, J.D.; Haslam, S.M.; Dell, A.
    High-sensitivity O-glycomic analysis of mice deficient in core 2 beta1,6-N-acetylglucosaminyltransferases (2011), Glycobiology, 21, 82-98.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.1.148

Organism

Organism UniProt Comment Textmining
Mus musculus
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Source Tissue

Source Tissue Comment Organism Textmining
colon isoform C2GnT2 is highly expressed mainly in the stomach and the colon Mus musculus
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liver isoform C2GnT3 is highly expressed mainly in the small intestine, liver and spleen Mus musculus
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additional information isoform C2GnT1 is widely expressed in most tissues Mus musculus
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small intestine isoform C2GnT3 is highly expressed mainly in the small intestine, liver and spleen Mus musculus
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spleen isoform C2GnT3 is highly expressed mainly in the small intestine, liver and spleen Mus musculus
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stomach isoform C2GnT2 is highly expressed mainly in the stomach and the colon Mus musculus
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Synonyms

Synonyms Comment Organism
C2GnT
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 Mus musculus
C2GnT1 isoform Mus musculus
C2GnT2 isoform Mus musculus
C2GnT3 isoform Mus musculus
core 2 beta1,6-N-acetylglucosaminyltransferase
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 Mus musculus

General Information

General Information Comment Organism
malfunction the triple knockout mice lack the ability to synthesize all three known isoforms of core 2 beta1,6-N-acetylglucosaminyltransferase. This multiple deficiency causes a complete absence of core 2 O-glycans in the colon Mus musculus