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Literature summary for 2.4.1.141 extracted from
- Alg14 recruits Alg13 to the cytoplasmic face of the endoplasmic reticulum to form a novel bipartite UDP-N-acetylglucosamine transferase required for the second step of N-linked glycosylation (2005), J. Biol. Chem., 280, 36254-36262.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| endoplasmic reticulum | Alg 14 protein functions as a membrane anchor that recruits Alg 13 protein to the cytosolic face of the endoplasmic reticulum, where catalysis of GlcNAc2-PP-dol occurs. Alg 13 protein and Alg 14 protein physically interact and under normal conditions, are associated with the membrane of the endoplasmic reticulum | Saccharomyces cerevisiae | 5783 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| N-acetyl-D-glucosaminyl-diphosphodolichol + UDP-glucuronic acid | Saccharomyces cerevisiae | - |
D-glucuronyl-1,4-N-acetyl-D-glucosaminyl-diphosphodolichol + UDP | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| N-acetyl-D-glucosaminyl-diphosphodolichol + UDP-glucuronic acid | - |
Saccharomyces cerevisiae | D-glucuronyl-1,4-N-acetyl-D-glucosaminyl-diphosphodolichol + UDP | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | Alg 14 protein functions as a membrane anchor that recruits Alg 13 protein to the cytosolic face of the ER, where catalysis of GlcNAc2-PP-dol occurs. Alg 13 protein and Alg 14 protein physically interact and under normal conditions, are associated with the membrane of the endoplasmic reticulum | Saccharomyces cerevisiae |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Alg 14 | - |
Saccharomyces cerevisiae |
| Alg13 | - |
Saccharomyces cerevisiae |
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Release 2023.1 (January 2023)
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