Any feedback?
Literature summary for 2.4.1.135 extracted from
- Biosynthesis of heparin. Solubilization and partial purification of uridine diphosphate glucuronic acid: acceptor glucuronosyltransferase from mouse mastocytoma (1972), J. Biol. Chem., 247, 4327-4332.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00025 | - |
UDPglucuronate | - |
Mus musculus |  |
| 0.0091 | - |
3-beta-galactosyl-galactose | - |
Mus musculus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | bound | Mus musculus | 16020 | - |
| microsome | - |
Mus musculus | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mn2+ | required | Mus musculus | |
| Mn2+ | 20 mM | Mus musculus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| UDPglucuronate + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein | Mus musculus | involved in the biosynthesis of the heparin-polypeptide linkage region | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Mus musculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| mastocytoma cell | - |
Mus musculus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Mus musculus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | galactosyl-beta-1,4-xylose, galactosyl-beta-1,4-glucose is a less effective acceptor substrate | Mus musculus | ? | - |
? | |
| additional information | galactosyl-beta-1,6-galactose is a less effective acceptor substrate | Mus musculus | ? | - |
? | |
| UDPglucuronate + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein | involved in the biosynthesis of the heparin-polypeptide linkage region | Mus musculus | ? | - |
? | |
| UDPglucuronate + 3-beta-D-galactosyl-D-galactose | - |
Mus musculus | UDP + 3-beta-D-glucuronosyl-3-beta-D-galactosyl-D-galactose | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
- |
Mus musculus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 6.5 | 8.5 | about 50% of maximal activity at pH 6.5 and pH 8.5 | Mus musculus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
