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Literature summary for 2.4.1.133 extracted from

  • Gu, J.; Fan, J.; Xu, Y.; Xie, Y.; Gong, T.; Kong, Y.
    Regulatory function of beta1,4-galactosyltransferase I expression on Lewis-Y glycan and embryo implantation (2015), Gene, 562, 220-225.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
quantitative enzyme expression analysis by RT-PCR Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
Golgi apparatus
-
Homo sapiens 5794
-

Organism

Organism UniProt Comment Textmining
Homo sapiens P15291
-
-

Source Tissue

Source Tissue Comment Organism Textmining
embryo
-
Homo sapiens
-
RL95-2 cell human uterine epithelial cells Homo sapiens
-
uterine endometrium
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme catalyzes the transfer of galactose from uridine diphosphogalactose to terminal N-acetylglucosamine, forming the Galbeta1-4GlcNAc structure Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
beta1,4-galactosyltransferase I
-
Homo sapiens
beta1,4-GalT-I
-
Homo sapiens

General Information

General Information Comment Organism
physiological function beta1,4-Galactosyltransferase I is a key enzyme in glycobiology mediating several biological mechanisms. The enzyme possibly regulate mutual uterus-embryo adhesion and embryo implantation by regulating cell surface Lewis-Y glycan expression Homo sapiens