Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.4.1.122 extracted from

  • Brockhausen, I.; M๖ller, G.; Pollex-Kruger, A.; Rutz, V.; Paulsen, H.; Matta, K.L.
    Control of O-glycan synthesis: specificity and inhibition of O-glycan core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 3-galactosyltransferase from rat liver (1992), Biochem. Cell Biol., 70, 99-108.
    View publication on PubMed
Search for more literature for 2.4.1.122

Inhibitors

Inhibitors Comment Organism Structure
6-O-(4,4-azo)phenyl-GalNAc-alpha-benzyl
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-galactose + glycoprotein N-acetyl-D-galactosamine Rattus norvegicus major control factor in the biosynthesis of O-glycans UDP + glycoprotein D-galactosyl-1,3-N-acetyl-D-galactosamine
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-galactose + glycoprotein N-acetyl-D-galactosamine glycosyl acceptor specificity study Rattus norvegicus UDP + glycoprotein D-galactosyl-1,3-N-acetyl-D-galactosamine
-
 ?
UDP-galactose + glycoprotein N-acetyl-D-galactosamine major control factor in the biosynthesis of O-glycans Rattus norvegicus UDP + glycoprotein D-galactosyl-1,3-N-acetyl-D-galactosamine
-
 ?
UDP-galactose + N-acetyl-alpha-D-galactosaminyl-benzyl removal or substitution of the 3-OH group or removal of the 4-OH group abolishes enzyme activity, removal or substitution of the 6-OH reduces activity slightly leading to competititve substrates Rattus norvegicus UDP + beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-benzyl
-
 ?
UDP-galactose + N-acetylgalactosaminide mucin
-
 Rattus norvegicus UDP + beta-D-galactosyl-1,3-N-acetylgalactosaminide mucin
-
 ?

Synonyms

Synonyms Comment Organism
UDP-Gal:N-acetylgalactosaminide mucin:beta1,3-galactosyltransferase
-
 Rattus norvegicus