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Literature summary for 2.4.1.1 extracted from

  • Dudash, J.; Zhang, Y.; Moore, J.B.; Look, R.; Liang, Y.; Beavers, M.P.; Conway, B.R.; Rybczynski, P.J.; Demarest, K.T.
    Synthesis and evaluation of 3-anilino-quinoxalinones as glycogen phosphorylase inhibitors (2005), Bioorg. Med. Chem. Lett., 15, 4790-4793.
    View publication on PubMed
Search for more literature for 2.4.1.1

Inhibitors

Inhibitors Comment Organism Structure
1-methyl-3-([4-(2-thienylmethyl)phenyl]amino)quinoxalin-2(1H)-one 50% inhibition at 0.00011 mM in glycogenolysis assay, no bioavailability in vivo Rattus norvegicus
3-[(4-isoxazolidin-3-ylphenyl)amino]-1-methylquinoxalin-2(1H)-one 50% inhibition at 0.00011 mM in glycogenolysis assay, no bioavailability in vivo Rattus norvegicus
4-[(4-methyl-3-oxo-3,4-dihydroquinoxalin-2-yl)amino]-N-(2-thienylmethyl)benzamide 50% inhibition at 0.00014 mM in glycogenolysis assay, no bioavailability in vivo Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hepatocyte
-
 Rattus norvegicus
-