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Literature summary for 2.4.1.1 extracted from
- Cell volume affects glycogen phosphorylase activity in fish hepatocytes (2003), J. Comp. Physiol. B, 173, 591-599.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| DMSO | strong activation of enzyme in hepatocytes | Ameiurus nebulosus |  |
| ethanol | strong activation of enzyme in hepatocytes | Ameiurus nebulosus | |
| additional information | activity is increased in hyperosmotic media by 7fold, activation is not influenced by EDTA or 8-bromo-Rp-cAMP | Ameiurus nebulosus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | activity is decreased in hyposmotic media | Ameiurus nebulosus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (1,4-alpha-D-glucosyl)n + phosphate | Ameiurus nebulosus | polysaccharide substrate is glycogen | (1,4-alpha-D-glucosyl)n-1 + alpha-D-glucose 1-phosphate | - |
? | |
| additional information | Ameiurus nebulosus | the cell volume affects the activity in hepatocytes, thus the enzyme activity is a function of medium osmolarity, activity is increased in hyperosmotic media, overview | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Ameiurus nebulosus | - |
brown bullhead catfish | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
activities in media with different osmolarity | Ameiurus nebulosus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (1,4-alpha-D-glucosyl)n + phosphate | polysaccharide substrate is glycogen | Ameiurus nebulosus | (1,4-alpha-D-glucosyl)n-1 + alpha-D-glucose 1-phosphate | - |
? | |
| (1,4-alpha-D-glucosyl)n + phosphate | polysaccharide substrate is bovine liver glycogen | Ameiurus nebulosus | (1,4-alpha-D-glucosyl)n-1 + alpha-D-glucose 1-phosphate | - |
? | |
| additional information | the cell volume affects the activity in hepatocytes, thus the enzyme activity is a function of medium osmolarity, activity is increased in hyperosmotic media, overview | Ameiurus nebulosus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| glycogen phosphorylase | - |
Ameiurus nebulosus |
| GPase | - |
Ameiurus nebulosus |
| GPase a | active enzyme form | Ameiurus nebulosus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 21 | - |
assay at | Ameiurus nebulosus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.5 | - |
assay at | Ameiurus nebulosus |
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Release 2023.1 (January 2023)
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