Activating Compound | Comment | Organism | Structure |
---|---|---|---|
5'-AMP | activation | Oryctolagus cuniculus | |
IMP | 0.1 mM, half-maximal activation of phosphorylase ab | Oryctolagus cuniculus | |
phosphate | activation | Oryctolagus cuniculus | |
Phosphorylase kinase | activation | Oryctolagus cuniculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
D-glucose | 5 mM and 8.5 mM, 50% inhibition of phosphorylase ab at 8 mM and 16 mM glucose 1-phosphate, 23 mM and 40 mM, 50% inhibition of phosphorylase a | Oryctolagus cuniculus | |
glucose 6-phosphate | - |
Oryctolagus cuniculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinetic data | Oryctolagus cuniculus | |
3.56 | - |
glucose 1-phosphate | phosphorylase a | Oryctolagus cuniculus | |
18 | - |
glucose 1-phosphate | phosphorylase ab | Oryctolagus cuniculus | |
20 | - |
glucose 1-phosphate | phosphorylase ab | Oryctolagus cuniculus | |
28 | - |
phosphate | phosphorylase ab | Oryctolagus cuniculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
side-chain modification | activation by phosphorylation | Oryctolagus cuniculus |
Purification (Comment) | Organism |
---|---|
phosphorylase ab hybrid | Oryctolagus cuniculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
muscle | skeletal muscle | Oryctolagus cuniculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glycogen + glucose 1-phosphate | - |
Oryctolagus cuniculus | glycogen + phosphate | - |
r | |
[(1->4)-alpha-D-glucosyl]n + phosphate | - |
Oryctolagus cuniculus | [(1->4)-alpha-D-glucosyl]n-1 + alpha-D-glucose 1-phosphate | - |
r |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
1.5 | - |
glucose 6-phosphate | phosphorylase ab | Oryctolagus cuniculus | |
4.5 | - |
glucose | phosphorylase ab and a | Oryctolagus cuniculus |