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Literature summary for 2.3.3.8 extracted from

  • Xing, S.; van Deenen, N.; Magliano, P.; Frahm, L.; Forestier, E.; Nawrath, C.; Schaller, H.; Gronover, C.S.; Pruefer, D.; Poirier, Y.
    ATP citrate lyase activity is post-translationally regulated by sink strength and impacts the wax, cutin and rubber biosynthetic pathways (2014), Plant J., 79, 270-284.
    View publication on PubMed
Search for more literature for 2.3.3.8

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Arabidopsis thaliana and in laticifer of roots of dandelion Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Arabidopsis thaliana 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ADP + phosphate + acetyl-CoA + oxaloacetate Arabidopsis thaliana
-
 ATP + citrate + CoA
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
 ecotype Columbia
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + phosphate + acetyl-CoA + oxaloacetate
-
 Arabidopsis thaliana ATP + citrate + CoA
-
 ?

Synonyms

Synonyms Comment Organism
ACLA subunit Arabidopsis thaliana
ACLB subunit Arabidopsis thaliana
ATP citrate lyase
-
 Arabidopsis thaliana

General Information

General Information Comment Organism
physiological function enzyme overexpression in Arabidopsis is associated with a 30% increase in wax on stems, while overexpression of a chimeric homomeric enzyme in the laticifer of roots of dandelion leads to a 4 and 2fold increase in rubber and triterpene content, respectively Arabidopsis thaliana