Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
123000 | - |
x * 123000, SDS-PAGE | Rattus norvegicus |
500000 | - |
non-denaturing PAGE | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + citrate + CoA | Rattus norvegicus | the enzyme catalyzes the first cytoplasmic step in the synthesis of long-chain fatty acids in mammalian tissues | ADP + phosphate + acetyl-CoA + oxaloacetate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
liver enzyme | Rattus norvegicus |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA | double-displacement mechanism with a phosphoenzyme intermediate | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
13.6 | - |
- |
Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + citrate + CoA | - |
Rattus norvegicus | ADP + phosphate + acetyl-CoA + oxaloacetate | - |
? | |
ATP + citrate + CoA | the enzyme catalyzes the first cytoplasmic step in the synthesis of long-chain fatty acids in mammalian tissues | Rattus norvegicus | ADP + phosphate + acetyl-CoA + oxaloacetate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 123000, SDS-PAGE | Rattus norvegicus |