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Literature summary for 2.3.3.3 extracted from

  • O'Brien, R.W.; Stern, J.R.
    Reversal of the stereospecificity of the citrate synthase of Clostridium kluyveri by p-chloromercuribenzoate (1969), Biochem. Biophys. Res. Commun., 34, 271-276.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
4-chloromercuribenzoate 1 mM and 5 mM, 35 and 42% inhibition in extracts of Barker strain, respectively Clostridium kluyveri

Organism

Organism UniProt Comment Textmining
Clostridium kluyveri
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + H2O + oxaloacetate stereospecificity of citrate synthase in extracts can be changed reversibly from the (R)-type to the (S)-type by treatment with 4-chloromercuribenzoate Clostridium kluyveri citrate + CoA
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