Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.3.16 extracted from

  • Brock, M.; Fischer, R.; Linder, D.; Buckel, W.
    Methylcitrate synthase from Aspergillus nidulans: implications for propionate as an antifungal agent (2000), Mol. Microbiol., 35, 961-973.
    View publication on PubMed
Search for more literature for 2.3.3.16

Cloned(Commentary)

Cloned (Comment) Organism
cloning and expression in Aspergillus nidulans, DNA sequence Aspergillus nidulans

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0017
-
 propionyl-CoA methylcitrate synthase exhibiting also citrate synthase activity Aspergillus nidulans
0.0025
-
 acetyl-CoA methylcitrate synthase exhibiting also citrate synthase activity Aspergillus nidulans
0.63
-
 oxaloacetate with propionyl-CoA, methylcitrate synthase exhibiting also citrate synthase activity Aspergillus nidulans

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
additional information
-
 amino acid sequence Aspergillus nidulans

Organism

Organism UniProt Comment Textmining
Aspergillus nidulans Q9TEM3 methylcitrate synthase, also exhibiting citrate synthase activity
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
41.5
-
 citrate synthase activity of a purified methylcitrate synthase Aspergillus nidulans

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + oxaloacetate + H2O
-
 Aspergillus nidulans citrate + CoA
-
 ?
propionyl-CoA + oxaloacetate + H2O methylcitrase synthase, also exhibiting citrate synthase activity Aspergillus nidulans 2-methylcitrate + CoA
-
 ?