Literature summary for 2.3.3.14 extracted from

Feller, A.; Ramos, F.; Pierard, A.; Dubois, E.
In Saccharomyces cerevisiae, feedback inhibition of homocitrate synthase by lysine modulates the activation of LYS gene expression by Lys14p (1999), Eur. J. Biochem., 261, 163-170.

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Inhibitors

Inhibitors	Comment	Organism	Structure
L-Lys	feedback inhibition of homocitrate synthase by lysine modulates the activation of LYS gene expression by transcriptional activator Lys14p	Saccharomyces cerevisiae

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
nucleus	two isoenzymes are located in the nucleus	Saccharomyces cerevisiae	5634	-

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
acetyl-CoA + H2O + 2-oxoglutarate	-	Saccharomyces cerevisiae	2-hydroxybutane-1,2,4-tricarboxylate + CoA	-	?

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Release 2023.1 (January 2023)