Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Selenalysine | 7.5 mM, 90% inhibition, half-maximal inhibition at 1.9 mM, competitive inhibition against both acetyl-CoA and 2-oxoglutarate | Wickerhamomyces anomalus | |
thialysine | competitive with acetyl-CoA | Wickerhamomyces anomalus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Wickerhamomyces anomalus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + H2O + 2-oxoglutarate | - |
Wickerhamomyces anomalus | 2-hydroxybutane-1,2,4-tricarboxylate + CoA | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.14 | - |
Selenalysine | competitive against 2-oxoglutarate | Wickerhamomyces anomalus | |
0.94 | - |
L-thialysine | competitive against acetyl-CoA | Wickerhamomyces anomalus | |
1.1 | - |
Selenalysine | competitive against acetyl-CoA | Wickerhamomyces anomalus |