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Literature summary for 2.3.3.14 extracted from

  • Shimizu, E.; Yamana, R.; Tanaka, H.; Soda, K.
    Effects of a selenium analogue of L-lysine on growth of Candida pelliculosa (1984), Agric. Biol. Chem., 48, 2871-2872.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
Selenalysine 7.5 mM, 90% inhibition, half-maximal inhibition at 1.9 mM, competitive inhibition against both acetyl-CoA and 2-oxoglutarate Wickerhamomyces anomalus
thialysine competitive with acetyl-CoA Wickerhamomyces anomalus

Organism

Organism UniProt Comment Textmining
Wickerhamomyces anomalus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + H2O + 2-oxoglutarate
-
Wickerhamomyces anomalus 2-hydroxybutane-1,2,4-tricarboxylate + CoA
-
?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.14
-
Selenalysine competitive against 2-oxoglutarate Wickerhamomyces anomalus
0.94
-
L-thialysine competitive against acetyl-CoA Wickerhamomyces anomalus
1.1
-
Selenalysine competitive against acetyl-CoA Wickerhamomyces anomalus