Inhibitors | Comment | Organism | Structure |
---|---|---|---|
L-leucine | linear, non-competitive feedback inhibition | Mycobacterium tuberculosis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + alpha-ketoisovalerate + H2O | Mycobacterium tuberculosis | first step of leucine biosynthesis | alpha-isopropylmalate + CoA | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + alpha-ketoisovalerate + H2O | first step of leucine biosynthesis | Mycobacterium tuberculosis | alpha-isopropylmalate + CoA | - |
? | |
acetyl-CoA + alpha-ketoisovalerate + H2O | aldol condensation reaction | Mycobacterium tuberculosis | alpha-isopropylmalate + CoA | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.017 | - |
L-leucine | - |
Mycobacterium tuberculosis |