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Literature summary for 2.3.2.B11 extracted from

  • Ziegenhagen, R.; Goldberg, M.; Rakutt, W.D.; Jennissen, H.P.
    Multiple ubiquitination of calmodulin results in one polyubiquitin chain linked to calmodulin (1990), FEBS Lett., 271, 71-75.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ required Oryctolagus cuniculus

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
reticulocyte
-
Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
[RING-E3-ubiquitin-carrier protein]-S-ubiquitinyl-L-cysteine + [calmodulin]-L-lysine up to 3 molecules of ubiquitin can be incorporated into one molecule of calmodulin. If methylated ubiquitin is employed only one conjugate corresponding to the mono-ubiquitination product of calmodulin is formed. Only a single Lys residue in calmodulin is conjugated to ubiquitin. All other higher molecular weight ubiquitin-calmodulin conjugates must therefore be composed of one calmodulin to which an oligo- or polyubiquitin chain is linked Oryctolagus cuniculus [RING-E3-ubiquitin-carrier protein]-L-cysteine + [calmodulin]-N6-ubiquitinyl-L-lysine up to 3 molecules of ubiquitin can be incorporated into one molecule of calmodulin. If methylated ubiquitin is employed only one conjugate corresponding to the mono-ubiquitination product of calmodulin is formed. Only a single Lys residue in calmodulin is conjugated to ubiquitin. All other higher molecular weight ubiquitin-calmodulin conjugates must therefore be composed of one calmodulin to which an oligo- or polyubiquitin chain is linked ?