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Literature summary for 2.3.2.8 extracted from

  • Wang, J.; Han, X.; Saha, S.; Xu, T.; Rai, R.; Zhang, F.; Wolf, Y.I.; Wolfson, A.; Yates, J.R.; Kashina, A.
    Arginyltransferase is an ATP-independent self-regulating enzyme that forms distinct functional complexes in vivo (2011), Chem. Biol., 18, 121-130.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.2.8

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Mus musculus 5829
-
ribosome
-
 Mus musculus 5840
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
60000
-
 x * 60000, isoform ATE1-2, SDS-PAGE Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA column chromatography Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-arginyl-tRNAArg + bovine alpha-lactalbumin higher activity is detected with isoforms ATE1-1 (100%) and ATE1-2 (85%), and weaker activity is detected with isoforms ATE1-3 (18%) and ATE1-4 (4%) Mus musculus tRNAArg + L-arginyl-[bovine alpha-lactalbumin]
-
 ?
L-arginyl-tRNAArg + bovine serum albumin high activity is detected with isoforms ATE1-1 (100%) and ATE1-2 (95%), and weaker activity is detected with isoforms ATE1-3 (10%) and ATE1-4 (4%) Mus musculus tRNAArg + L-arginyl-[bovine serum albumin]
-
 ?
additional information ATE1 is capable of self-arginylation in vitro and in vivo Mus musculus ?
-
 ?
additional information the arginylation reaction does not require the formation of an ATE1-arginyl-tRNA synthetase complex or the presence of ATP Mus musculus ?
-
 ?

Subunits

Subunits Comment Organism
? x * 60000, isoform ATE1-2, SDS-PAGE Mus musculus

Synonyms

Synonyms Comment Organism
Ate1
-
 Mus musculus
ATE1-1 isoform Mus musculus
ATE1-2 isoform Mus musculus
Ate1-3 isoform Mus musculus
Ate1-4 isoform Mus musculus

Cofactor

Cofactor Comment Organism Structure
additional information the enzyme is independent of ATP Mus musculus