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Literature summary for 2.3.2.6 extracted from

  • Soffer, R.L.
    Peptide acceptors in the leucine, phenylalanine transfer reaction (1973), J. Biol. Chem., 248, 8424-8428.
    View publication on PubMed
Search for more literature for 2.3.2.6

General Stability

General Stability Organism
Stable to repeated freeze-thawing Escherichia coli

Inhibitors

Inhibitors Comment Organism Structure
Arg inhibition of alpha-S1-casein-dependent reaction Escherichia coli
Arg-Ala inhibition of alpha-S1-casein-dependent reaction Escherichia coli
Arg-Arg inhibition of alpha-S1-casein-dependent reaction Escherichia coli
Arg-Asp inhibition of alpha-S1-casein-dependent reaction Escherichia coli
Arg-Glu inhibition of alpha-S1-casein-dependent reaction Escherichia coli
Arg-Gly inhibition of alpha-S1-casein-dependent reaction Escherichia coli
Arg-Gly-Gly inhibition of alpha-S1-casein-dependent reaction Escherichia coli
Arg-Leu inhibition of alpha-S1-casein-dependent reaction Escherichia coli
Arg-Lys inhibition of alpha-S1-casein-dependent reaction Escherichia coli
Arg-Phe inhibition of alpha-S1-casein-dependent reaction Escherichia coli
Arg-Tyr inhibition of alpha-S1-casein-dependent reaction Escherichia coli
Arg-Val inhibition of alpha-S1-casein-dependent reaction Escherichia coli
Arginine methyl ester inhibition of alpha-S1-casein-dependent reaction Escherichia coli
L-lysyl-L-serine inhibition of alpha-S1-casein-dependent reaction Escherichia coli
Lys inhibition of alpha-S1-casein-dependent reaction Escherichia coli
Lys-Ala inhibition of alpha-S1-casein-dependent reaction Escherichia coli
Lys-Ala-Ala inhibition of alpha-S1-casein-dependent reaction Escherichia coli
Lys-Glu inhibition of alpha-S1-casein-dependent reaction Escherichia coli
Lys-Gly
-
 Escherichia coli
Lys-Leu inhibition of alpha-S1-casein-dependent reaction Escherichia coli
Lys-Phe inhibition of alpha-S1-casein-dependent reaction Escherichia coli
Lys-Tyr-Thr inhibition of alpha-S1-casein-dependent reaction Escherichia coli
Lys-Val inhibition of alpha-S1-casein-dependent reaction Escherichia coli

Localization

Localization Comment Organism GeneOntology No. Textmining
soluble
-
 Escherichia coli
-
-

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
 B
-
Escherichia coli B / ATCC 11303
-
 B
-

Purification (Commentary)

Purification (Comment) Organism
-
 Escherichia coli

Storage Stability

Storage Stability Organism
-20°C, stable for at least 6 months Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-leucyl-tRNALeu + protein acceptor protein: alphaS1-casein Escherichia coli tRNALeu + L-leucyl-protein
-
 ?
L-leucyl-tRNALeu + protein all peptides containing a NH2-terminal L-Arg or Lys residue function as acceptor, however D-Arg-D-Val is inactive Escherichia coli tRNALeu + L-leucyl-protein
-
 ?
L-leucyl-tRNALeu + protein basic NH2-terminal is absolute determinant of specificity Escherichia coli tRNALeu + L-leucyl-protein
-
 ?
L-leucyl-tRNALeu + protein acceptor protein: alphaS1-casein Escherichia coli B / ATCC 11303 tRNALeu + L-leucyl-protein
-
 ?
L-leucyl-tRNALeu + protein all peptides containing a NH2-terminal L-Arg or Lys residue function as acceptor, however D-Arg-D-Val is inactive Escherichia coli B / ATCC 11303 tRNALeu + L-leucyl-protein
-
 ?
L-leucyl-tRNALeu + protein basic NH2-terminal is absolute determinant of specificity Escherichia coli B / ATCC 11303 tRNALeu + L-leucyl-protein
-
 ?
L-phenylalanyl-tRNA + acceptor protein
-
 Escherichia coli tRNA + L-phenylalanyl-protein
-
 ?
L-phenylalanyl-tRNA + acceptor protein
-
 Escherichia coli B / ATCC 11303 tRNA + L-phenylalanyl-protein
-
 ?
L-phenylalanyl-tRNA + Lys-Ala-Ala
-
 Escherichia coli Phe-Lys-Ala-Ala + tRNA
-
 ?
L-phenylalanyl-tRNA + Lys-Ala-Ala
-
 Escherichia coli B / ATCC 11303 Phe-Lys-Ala-Ala + tRNA
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.2
-
 Arg-Lys inhibition of reaction with alphaS1-casein as acceptor Escherichia coli
0.4
-
 Arg-Arg inhibition of reaction with alphaS1-casein as acceptor Escherichia coli
0.4
-
 Arg-Gly-Gly inhibition of reaction with alphaS1-casein as acceptor Escherichia coli
1
-
 Arg-Val inhibition of reaction with alphaS1-casein as acceptor Escherichia coli
1.3
-
 Arg-Gly inhibition of reaction with alphaS1-casein as acceptor Escherichia coli
1.4
-
 Arg-Phe inhibition of reaction with alphaS1-casein as acceptor Escherichia coli
1.5
-
 Arginine methyl ester inhibition of reaction with alphaS1-casein as acceptor Escherichia coli
1.5
-
 Arg-Ala inhibition of reaction with alphaS1-casein as acceptor Escherichia coli
1.6
-
 Arg-Tyr inhibition of reaction with alphaS1-casein as acceptor Escherichia coli
3
-
 Lys-Ala-Ala inhibition of reaction with alphaS1-casein as acceptor Escherichia coli
3.5
-
 Arg-Leu inhibition of reaction with alphaS1-casein as acceptor Escherichia coli
3.6
-
 Lys-Ala inhibition of reaction with alphaS1-casein as acceptor Escherichia coli
4
-
 Lys-Phe inhibition of reaction with alphaS1-casein as acceptor Escherichia coli
4
-
 Lys-Val inhibition of reaction with alphaS1-casein as acceptor Escherichia coli
6
-
 Lys-Gly inhibition of reaction with alphaS1-casein as acceptor Escherichia coli
6
-
 Arg-Asp inhibition of reaction with alphaS1-casein as acceptor Escherichia coli
6.3
-
 Lys-Tyr-Thr inhibition of reaction with alphaS1-casein as acceptor Escherichia coli
7.5
-
 Arg-Glu inhibition of reaction with alphaS1-casein as acceptor Escherichia coli
7.8
-
 Lys-Leu inhibition of reaction with alphaS1-casein as acceptor Escherichia coli
10
-
 arginine inhibition of reaction with alphaS1-casein as acceptor Escherichia coli
10
-
 Lys-Ser inhibition of reaction with alphaS1-casein as acceptor Escherichia coli
15
-
 Lys-Glu inhibition of reaction with alphaS1-casein as acceptor Escherichia coli