Application | Comment | Organism |
---|---|---|
medicine | the enzyme is a pharmacological target for Alzheimers disease therapy | Mus musculus |
medicine | the enzyme is a pharmacological target for Alzheimers disease therapy | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hippocampus | - |
Mus musculus | - |
hippocampus | - |
Homo sapiens | - |
neuron | - |
Mus musculus | - |
neuron | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Gln-2-naphthylamide | - |
Mus musculus | 5-oxoprolyl-2-naphthylamide + NH3 | - |
? | |
L-Gln-2-naphthylamide | - |
Homo sapiens | 5-oxoprolyl-2-naphthylamide + NH3 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
glutaminyl cyclase | - |
Mus musculus |
glutaminyl cyclase | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | glutaminyl cyclase contributes to the formation of focal and diffuse diglutamate-Abeta peptide deposits in hippocampus | Mus musculus |
physiological function | glutaminyl cyclase contributes to the formation of focal and diffuse diglutamate-Abeta peptide deposits in hippocampus | Homo sapiens |