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Literature summary for 2.3.2.2 extracted from

  • Lherbet, C.; Gravel, C.; Keillor, J.W.
    Synthesis of S-alkyl L-homocysteine analogues of glutathione and their kinetic studies with gamma-glutamyl transpeptidase (2004), Bioorg. Med. Chem. Lett., 14, 3451-3455.
    View publication on PubMed
Search for more literature for 2.3.2.2

Inhibitors

Inhibitors Comment Organism Structure
(2S)-2-amino-4-((3-((carboxymethyl)amino)-3-oxopropyl)sulfinyl)butanoic acid competitive Rattus norvegicus
(2S)-2-amino-4-((3-((carboxymethyl)amino)-3-oxopropyl)sulfonyl)butanoic acid
-
 Rattus norvegicus
(2S)-2-amino-4-((3-((carboxymethyl)amino)-3-oxopropyl)thio)butanoic acid competitive Rattus norvegicus
(2S)-2-amino-4-((4-(((carboxymethyl)amino)carbonyl)benzyl)sulfinyl)butanoic acid competitive Rattus norvegicus
L-Met competitive Rattus norvegicus
L-methionine sulfoxide competitive Rattus norvegicus
additional information no inhibition by L-methionine sulfone Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Rattus norvegicus
-

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.053
-
 (2S)-2-amino-4-((3-((carboxymethyl)amino)-3-oxopropyl)sulfinyl)butanoic acid
-
 Rattus norvegicus
0.23
-
 (2S)-2-amino-4-((4-(((carboxymethyl)amino)carbonyl)benzyl)sulfinyl)butanoic acid
-
 Rattus norvegicus
0.52
-
 (2S)-2-amino-4-((3-((carboxymethyl)amino)-3-oxopropyl)thio)butanoic acid
-
 Rattus norvegicus
3.5
-
 (2S)-2-amino-4-((3-((carboxymethyl)amino)-3-oxopropyl)sulfonyl)butanoic acid
-
 Rattus norvegicus
5.9
-
 L-methionine sulfoxide
-
 Rattus norvegicus
26.9
-
 L-Met
-
 Rattus norvegicus